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Indoximod A methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. Synonyms: NLG8189; NLG 8189; NLG-8189; D-1MT; 1-methyl-D-tryptophan; H-D-Trp(Me)-OH. Grades: > 98%. CAS No. 110117-83-4. Molecular formula: C12H14N2O2. Mole weight: 218.25. BOC Sciences 3
Indoximod Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase ( IDO ) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Methyl-D-tryptophan; NLG-8189. CAS No. 110117-83-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-16724. MedChemExpress MCE

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