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| Product | Description | |
|---|---|---|
| Iniparib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Iniparib | BSI-201 is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair. PARP-1 catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: BSI-201; BSI201; BSI 201; NSC746045; NSC-746045; NSC 746045; ND-71677; NIBA; INO-2BA; SAR-240550; IND-71677. IND 71677; IND71677; Iniparib. Grades: 99.82%. CAS No. 160003-66-7. Molecular formula: C7H5IN2O3. Mole weight: 292.032. |  |
| Iniparib | Iniparib (BSI-201) is an irreversible inhibitor of PARP1 , used in the research of triple negative breast cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSI-201; NSC-746045; IND-71677. CAS No. 160003-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12015. |  |
| Iniparib | Iniparib is an irreversible PARP1 inhibitor. Studies show that potential therapeutic agent for the treatment of cancer, including triple-negative breast cancer. Group: Biochemicals. Alternative Names: 4-Iodo-3-nitrobenzamide; BSI 201. Grades: Highly Purified. CAS No. 160003-66-7. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
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