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| Product | Description | |
|---|---|---|
| Inobrodib | Inobrodib (CCS1477) is an orally active, potent, and selective inhibitor of the p300/CBP bromodomain. Inobrodib binds to p300 and CBP with K d values of 1.3 and 1.7 nM, respectively, and with 170/130-fold selectivity compared with BRD4 with a K d of 222 nM. CCS1477 inhibits cell proliferation in prostate cancer cell lines and decreases androgen receptor (AR)- and C-MYC-regulated gene expression [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCS1477. CAS No. 2222941-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111784. |  |
| Inobrodib | Inobrodib is an inhibitor of the histone acetyltransferase p300 and CREB-binding protein and has antineoplastic activity. Synonyms: (6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]piperidin-2-one; (S)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1R,4S)-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one; CBP-IN-1; CCS-1477; (6S)-1-(3,4-Difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-2-piperidinone; CCS 1477; CCS1477. Grades: >98%. CAS No. 2222941-37-7. Molecular formula: C30H32F2N4O3. Mole weight: 534.60. |  |
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