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Inosine 5'-monophosphate. Group: Biochemicals. Alternative Names: Inosinic acid; IMP. Grades: Highly Purified. CAS No. 131-99-7. Pack Sizes: 500mg, 1g, 2g, 5g. Molecular Formula: C10H13N4O8P. US Biological Life Sciences.
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Inosine 5'-monophosphate
Inosine 5'-monophosphate (IMP) is a profound molecular compound magnanimously entrusted with the profound responsibility of studying an extensive array of afflictions, encompassing neurologic dysfunctions, cardiac anomalies and immunological imperfections. Synonyms: Inosinic acid; IMP; 1-5'-P; inosinemonophosphate; [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate. Grades: ≥ 98%. CAS No. 131-99-7. Molecular formula: C10H13N4O8P. Mole weight: 348.20.
Inosine 5'-monophosphate disodium salt
Disodium inosinate (E631) is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks. This salt is used as a flavor enhancer made from microbial fermentation growth media that are all-vegetable, usually consisting mainly of tapioca starch. Synonyms: Disodium 5'-inosinate; Disodium inosinate; Sodium Inosine 5'-Phosphate (2:1); 5'-Inosinic Acid Disodium Salt; 5'-IMP Disodium Salt; Disodium 5'-IMP; Disodium 5'-Inosinate; Disodium IMP; Disodium Inosinate; Disodium Inosine 5'-Monophosphate; Disodium Inosine 5'-Phosphate; IMP Disodium Salt; Inosine 5'-Monophosphate Disodium Salt; Inosine 5'-Monophosphoric Acid Disodium Salt. Grades: ≥97% by HPLC. CAS No. 4691-65-0. Molecular formula: C10H11N4Na2O8P. Mole weight: 392.17.
Inosine 5'-monophosphate disodium salt hydrate
Inosine 5'-monophosphate disodium salt hydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 4691-65-0,352195-40-5. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C10H11N4O8PNa2·xH2O. US Biological Life Sciences.
Worldwide
2'-Deoxyinosine 5'-monophosphate
2'-Deoxyinosine 5'-monophosphate, a vital biomolecule, intricately participates in the synthesis of DNA. With its involvement in the regulation of DNA replication and repair through the nucleotide dITP, this compound paves the way towards improved treatment processes. Notably, this biomolecule is also utilized in the management of autoimmune disorders inclusive of lupus and rheumatoid arthritis. Synonyms: Deoxyinosine monophosphate; 2''-Deoxyinosine-5''-monophosphoric acid; 2'-Deoxy-5'-inosinic acid; 2'-Deoxy-IMP; Hypoxanthine deoxyriboside; 9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grades: ≥98% by HPLC. CAS No. 3393-18-8. Molecular formula: C10H13N4O7P. Mole weight: 332.21.
2'-Deoxyinosine 5'-monophosphate disodium salt
2'-Deoxyinosine 5'-monophosphate disodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5'-Inosinic acid, 2'-deoxy-, disodium salt. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white solid. CAS No. 14999-52-1. Molecular formula: C10H11N4Na2O7P. Mole weight: 376.17. Purity: 0.98. IUPACName: Disodium;[(2R,3S,5R)-3-hydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate. Canonical SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=CNC3=O)COP(=O)([O-])[O-])O.[Na+].[Na+]. Product ID: ACM14999521. Alfa Chemistry ISO 9001:2015 Certified.
Inosine-3',5'-cyclic-monophosphate
Inosine-3',5'-cyclic-monophosphate, a multifaceted signaling molecule, participates in diverse physiological processes including muscle contraction, neurotransmission, and ion channel regulation. This intriguing biomolecule has captivated scientific attention for its prospective therapeutic applications in neurological disorders, cardiovascular pathologies, and malignant conditions. Its aptitude in promoting neuroprotection and augmenting synaptic plasticity renders it a fascinating candidate for tackling the symptoms of Alzheimer's and various other neurodegenerative afflictions. Synonyms: 3',5'-Cyclic IMP. CAS No. 3545-76-4. Molecular formula: C10H11N4O7P. Mole weight: 330.19.
Inosine-3',5'-cyclic-monophosphate free acid
Inosine-3',5'-cyclic-monophosphate free acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 3545-76-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C10H11N4O7P. US Biological Life Sciences.
Inosine-3',5'-cyclic-monophosphate triethylammonium is an indispensable compound extensively employed in the biomedical sector, operating as a pivotal second messenger in manifold cellular pathways. Its paramount significance lies in its indispensable role in studying signal transduction, gene expression and cellular metabolism, thereby facilitating research endeavors concerning drug development, particularly focused on cardiovascular, neurological and immune-related maladies. Molecular formula: C10H11N4O7P·NC6H15. Mole weight: 431.38.
Inosine-5'-monophosphate disodium salt heptahydrate
Inosine-5'-monophosphate disodium salt heptahydrate, an indispensable intermediate in purine biosynthesis, possesses a crucial role in nucleotide metabolism. Its applications primarily encompass functions such as treating gout and hyperuricemia while simultaneously enhancing the production of ribonucleotides. Synonyms: Sodium 5'-Inosinate hydrate (2:1:7). Grades: 98%. CAS No. 849725-39-9. Molecular formula: C10H25N4Na2O15P. Mole weight: 518.28.
Inosine-5'-monophosphate disodium salt hydrate, 99-103%
Inosine-5'-monophosphate disodium salt hydrate, 99-103%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Inosine-5-monophosphate disodium salt octahydrate
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP [1]. Uses: Scientific research. Group: Natural products. CAS No. 20813-76-7. Pack Sizes: 5 g. Product ID: HY-W010759.
Inosine-5'-monophosphate disodium salt octahydrate
Inosine-5'-monophosphate disodium salt octahydrate, a pivotal compound in biomedicine, holds immense significance due to its involvement in the biosynthesis of purine and nucleoside derivatives. Synonyms: 5'-IMP-Na2; Disodium 5'-inosinate octahydrate. Grades: 98%. CAS No. 20813-76-7. Molecular formula: C10H27N4Na2O16P. Mole weight: 536.29.
6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine-5'-monophosphate, Disodium Salt
Used in therapy of mouse leukemia L1210 in combinations with Nebularin and Nitrobenzylthioinosine 5'-monophosphate. Synonyms: 6-Nitrobenzylthioinosine 5'-Monophosphate Disodium Salt; 6-S-[(4-Nitrophenyl)methyl]-6-thio-5'-Inosinic Acid Disodium Salt. Grades: 98%. Molecular formula: C17H16N5Na2O9PS. Mole weight: 543.36.
6-Mercaptopurine-riboside-5'-monophosphate
6-Mercaptopurine-riboside-5'-monophosphate is a metabolite of 6-Mercaptopurine. Synonyms: 6-Thio-Inosine-5'-monophosphate; 6-Mercaptopurine-riboside-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 53-83-8. Molecular formula: C10H13N4O7PS (free acid). Mole weight: 364.26 (free acid).
IMP dehydrogenase
The enzyme acts on the hydroxy group of the hydrated derivative of the substrate. Group: Enzymes. Synonyms: inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase. Enzyme Commission Number: EC 1.1.1.205. CAS No. 9028-93-7. IMPDH2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0109; IMP dehydrogenase; EC 1.1.1.205; 9028-93-7; inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase. Cat No: EXWM-0109.
Inosine Monophosphate Dehydrogenase from Staphylococcus aureus, Recombinant
E.coli. Applications: Impdh is a recombinant protein of ca. 53kda cloned by pcr amplification of guab gene of staphylococcus aureus and expressed in e.coli. Group: Enzymes. Synonyms: inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase; IMP dehydrogenase; IMP:NAD+ oxidoreductase; EC 1.1.1.205; IMPDH. Enzyme Commission Number: EC 1.1.1.205. CAS No. 9028-93-7. IMPDH2. Mole weight: 53kDa. Activity: ≥ 0.3 unit/mg protein. Source: S. aureus. Species: IMPDH2. inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase; IMP dehydrogenase; IMP:NAD+ oxidoreductase; EC 1.1.1.205; IMPDH. Pack: stable lyophilized form. Cat No: NATE-1739.
Inosine Monophosphate Dehydrogenase Type II from Human, Recombinant
Type II is the predominant IMPDH isoform and is specifically linked to a wide range of cancers and lymphocyte proliferation. Group: Enzymes. Synonyms: inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase; IMP dehydrogenase; IMP:NAD+ oxidoreductase; EC 1.1.1.205; IMPDH II; IMPDH2; IMPD 2. Enzyme Commission Number: EC 1.1.1.205. CAS No. 231-791-2. IMPDH2. Storage: -70°C. Form: Solution in 20 mM Tris-HCl, pH 8.0, containing 0.5 mM EDTA and 1 mM DTT. Source: E. coli. Species: Human. inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase; IMP dehydrogenase; IMP:NAD+ oxidoreductase; EC 1.1.1.205; IMPDH II; IMPDH2; IMPD 2. Pack: vial of > 0.002 unit. Cat No: NATE-0352.
MANT-5'-IMP
MANT-5'-IMP is a fluorescent analogue of inosine-5'-monophosphate (λexc355 nm, λem448 nm). The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- / 3'- O- (N'- Methylanthraniloyl)inosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C18H20N5O9P (free acid). Mole weight: 481.4 (free acid).
Ribavirin
Ribavirin is a nucleoside analog that inhibits the replication of both DNA and RNA viruses, including influenza type A and type B. Ribavirin, as ribavirin 5-phosphate, affects virus-infected cells primarily by inhibiting the enzyme inosine 5-monophosphate (IMP) dehydrogenase. It potently suppresses eIF4E-mediated oncogenic transformation of murine cells in vitro, of tumor growth of a mouse model of eIF4E-dependent human squamous cell carcinoma in vivo, and of colony formation of eIF4E-dependent acute myelogenous leukemia cells derived from human patients. Group: Biochemicals. Alternative Names: 1-ß-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, ICN-1229, Rebetol, Viramid, Virazid, Virazole. Grades: Highly Purified. CAS No. 36791-04-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C8H12N4O5, Molecular Weight: 244.2. US Biological Life Sciences.
Worldwide
Ribavirin 5'-monophosphate lithium salt
Ribavirin 5'-monophosphate is a metabolite of ribavirin, displaying broad-spectrum antiviral activity. It inhibits viral DNA and RNA replication in vitro via suppression of inosine monophosphate dehydrogenase (IMPDH), resulting in inhibition of guanosine triphosphate synthesis. Synonyms: Dilithium [5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate. Grades: ≥95%. CAS No. 66983-94-6. Molecular formula: C8H11N4O8P·2Li. Mole weight: 336.1.
Ribavirin Monophosphate
Ribavirin-5'-monophosphate is a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase. In addition, Ribavirin 5'-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH) (Ki= 270 nM). Uses: Antiviral agents. Synonyms: Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 40925-28-8. Molecular formula: C8H13N4O8P (free acid). Mole weight: 324.18 (free acid).
5,7-dihydroxy-4-methylphthalide
5,7-dihydroxy-4-methylphthalide is an impurity of Mycophenolate Mofetil. Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Synonyms: 5,7-dihydroxy-4-methyl-3H-2-benzofuran-1-one. CAS No. 27979-57-3. Molecular formula: C9H8O4. Mole weight: 180.159.
BMS-566419
Potent inosine monophosphate dehydrogenase (IMPDH) inhibitor (IC50 = 17 nM). Inhibits proliferation of human T-lymphoblasts and PBMCs in vitro. Reduces paw swelling in a rat adjuvant arthritis model. Synonyms: BMS 566419; BMS566419; N-(1-(6-(4-Ethyl-1-piperazinyl)-3-pyridinyl)-1-methylethyl)-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide. Grades: >98%. CAS No. 566161-24-8. Molecular formula: C28H30FN5O2. Mole weight: 487.57.
cIMP, an intricate molecule that governs a multitude of fundamental cellular processes, stands out for its vital function in guanine nucleotide synthesis. Implicating its potential in the remediation of both cancer and inflammatory diseases, cIMP has marked its territory in the realm of pharmacological development. As researchers endeavor to ascertain a novel anti-cancer drug targeting this chemical entity, they also continue to investigate its promises in modulating immune function for the treatment of inflammatory bowel disease. Synonyms: Inosine-3',5'-cyclic monophosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H11N4O7P (free acid). Mole weight: 330.19 (free acid).
Diphosphoryl Chloride 90%
Diphosphoryl Chloride is used in the synthesis of potent and orally bioavailable tricyclic CGRP receptor antagonists. Also used in the synthesis of transition state analogue inhbitors of inosine monophosphate. Group: Biochemicals. Alternative Names: Pyrophosphoryl Chloride; Phosphorodichloridic Anhydride; Phosphorus Chloride Oxide; Pyrophosphoryl Tetrachloride; Tetra chloropyrophosphoric Acid. Grades: Highly Purified. CAS No. 13498-14-1. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Guanosine 5'-monophosphate disodium salt
Disodium guanylate, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). Disodium guanylate is a food additive with the E number E627. It is commonly used in conjunction with glutamic acid (monosodium glutamate, MSG). As it is a fairly expensive additive, it is not used independently of glutamic acid; if disodium guanylate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. It is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. Disodium guanylate is produced from dried seaweed and is often added to instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats, and packaged soup. Synonyms: Disodium guanylate; Disodium GMP; Disodium 5'-gmp; GMP disodium salt; 5'-Gmp disodium salt; Disodium guanosine-5'-monophosphate; 5'-Guanylic acid disodium salt; Sodium 5'-guanylate; Guanosine 5'-phosphate disodium salt. Grades: 98%. CAS No. 5550-12-9. Molecular formula: C10H12N5O8P·2Na. Mole weight: 407.18.
Inosine-3',5'-cyclic Monophosphate Sodium Salt
Inosine-3',5'-cyclic monophosphate is a cyclic nucleotide that stimulates steroidogenesis by adrenocortical cells in rats. Inosine-3',5'-cyclic monophosphate also stimulates insulin secretion in hamster pancreas cells. Synonyms: Inosine Cyclic 3',5'-(Hydrogen Phosphate) Sodium Salt; Inosine 3',5'-Phosphate (Cyclic) Sodium Salt; Inosine Cyclic 3',5'-(Hydrogen Phosphate) Monosodium Salt; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin Inosine Deriv.; 3',5'-cIMP Sodium Salt. Grades: 95%. CAS No. 41092-64-2. Molecular formula: C10H10N4NaO7P. Mole weight: 352.17.
Mycophenolate Mofetil
Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: RS 61443; TM-MMF. CAS No. 128794-94-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 1 g; 5 g. Product ID: HY-B0199.
Mycophenolate Mofetil-d4
Mycophenolate Mofetil-d 4 is the deuterium labeled Mycophenolate Mofetil. Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1132748-21-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0199S.
Mycophenolate mofetil hydrochloride
Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC 50 s of 39 nM and 27 nM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: RS 61443 hydrochloride; TM-MMF hydrochloride. CAS No. 116680-01-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0199A.
Mycophenolic acid
Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase ( IMPDH ) inhibitor with an EC 50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycophenolate. CAS No. 24280-93-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0421.
Mycophenolic acid acyl-b-D-glucuronide allyl ester, a highly significant compound extensively employed in the biomedical sector, plays a crucial role in the treatment of autoimmune disorders and the prevention of organ transplant rejection. By effectively impeding the inosine monophosphate dehydrogenase (IMPDH) enzyme, it showcases remarkable immunosuppressive characteristics, thereby curtailing the production of purine nucleotides. Synonyms: 1-[(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate] b-D-glucopyranuronic acid 2-propen-1-yl ester. CAS No. 860615-39-0. Molecular formula: C26H32O12. Mole weight: 536.53.
Mycophenolic Acid-d3 β-D-Glucuronide
A labeled metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. Group: Biochemicals. Alternative Names: 5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-(methoxy-d3)-7-methyl-3-oxo-4-isobenzofuranyl β-D-Glucopyranosiduronic Acid; Mycophenolic Acid-d3 Glucosiduronate; Mycophenolic Acid-d3 Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mycophenolic Acid Related Compound 1
An impurity of Mycophenolic which is a selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase. Synonyms: 5,7-Dihydroxy-4 methylphthhalide. Grades: > 95%. Molecular formula: C9H8O4. Mole weight: 180.16.
Mycophenolic acid sodium
Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase ( IMPDH ) inhibitor with an EC 50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycophenolate sodium. CAS No. 37415-62-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0421A.
Mycophenolic acid (Standard)
Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 24280-93-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0421R.
Native Rabbit Phosphorylase b
Phosphorylase b is a non-active form and is present in resting muscle. Phosphorylase b kinase activity increases significantly when the Mg2+:ATP ratio exceeds. The breakdown of ATP during muscle contraction is thought to trigger in vivo conversion of phosphorylase b into a. Phosphorylase b is activated by inosine monophosphate. Applications: Phosphorylase b is used to study the conversion mechanism of inactive phosphorylase b to active phosphorylase in muscle. phosphorylase b is used to study which factors influence the conversion of phosphorylase b to phosphorylase a such as temperature, amp, fluoride and detergents. it is used to study phosphorylase b deficiency mutations. t...α-glucan phosphorylase; 1,4-α-glucan phosphorylase; glucosan phosphorylase; granulose phosphorylase; maltodextrin phosphorylase; muscle phosphorylase; myophosphorylase; potato phosphorylase; starch phosphorylase; 1,4-α-D-glucan:phosphate α-D-glucosyltransferase; phosphorylase (ambiguous). Enzyme Commission Number: EC 2.4.1.1. CAS No. 9012-69-5. Purity: 2× crystallization. GPBB. Mole weight: mol wt 97.2 kDa by calculation. Activity: Type I, > 20 units/mg protein; Type II, > 7 units/mg. Storage: -20°C. Form: Type I, Lyophilized powder containing lactose, 5?-AMP, and Mg (OAc)2 (10 μmole per 100 mg protein); Type II, lyophilized powder, light yellow. Sour
phosphoribosylglycinamide formyltransferase
This THF dependent enzyme catalyzes a nucleophilic acyl substitution of the formyl group from 10-formyltetrahydrofolate (fTHF) to N1-(5-phospho-D-ribosyl)glycinamide (GAR) to form N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide (fGAR) as shown above. This reaction plays an important role in the formation of purine through the de novo purine biosynthesis pathway. This pathway creates inosine monophosphate (IMP), a precursor to adenosine monophosphate (AMP) and guanosine monophosphate (GMP). Group: Enzymes. Synonyms: 2-amino-N-ribosylacetamide 5'-phosphate transformylase; GAR formyltransferase; GAR transformylase; glycinamide ribonucleotide transformylase; GAR TFase; 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase. Enzyme Commission Number: EC 2.1.2.2. CAS No. 9032-2-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2004; phosphoribosylglycinamide formyltransferase; EC 2.1.2.2; 9032-02-4; 2-amino-N-ribosylacetamide 5'-phosphate transformylase; GAR formyltransferase; GAR transformylase; glycinamide ribonucleotide transformylase; GAR TFase; 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase. Cat No: EXWM-2004.
Ribavirin 2,3,5-Tri-O-acetyl
As a purine nucleoside analog, protected Ribavirin inhibits inosine monophosphate dehydrogenase. It could be used as an antiviral agent. This compound is suitable for pyruvate dehydrogenase (PDH) related research. Synonyms: 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide; Tri-O-acetylribavirin; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide. CAS No. 40372-03-0. Molecular formula: C14H18N4O8. Mole weight: 370.31.
Taribavirin hydrochloride
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A.
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