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| Product | Description | |
|---|---|---|
| Iobenguane | Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. Uses: Enzyme inhibitors. Synonyms: 3-Iodobenzylguanidine, 131I-MIBG, Azedra, I-131 MIBG, Iobenguane (131I) , Iobenguane I 131, MIBG, MIBG-(131 I), Ultratrace iobenguane I131. Grades: >98%. CAS No. 77679-27-7. Molecular formula: C8H10IN3. Mole weight: 279.095. |  |
| Iobenguane sulfate | Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIBG sulfate. CAS No. 87862-25-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129040A. |  |
| Iobenguane sulfate-I-131 | Iobenguane is used in a scintigraphy method called Metaiodobenzylguanidine (MIBG) scan as a radiopharmaceutical. It can localize to adrenergic tissue and thus can be used to identify the location of tumors like phaeochromocytomas and neuroblastomas. Iobenguane can also be used to eradicate tumor cells that take up and metabolize norepinephrine. Phase II Clinical trials for the treatment of Neuroblastoma is on-going. Uses: Neuroblastoma; metaiodobenzylguanidine scan. Synonyms: ((3-(iodo-(sup 123)I)phenyl)methyl)-Guanidine sulfate (2:1). Grades: 98%. CAS No. 139755-80-9. Molecular formula: C16H20[123I]2N6.O4SH2. Mole weight: 640.27. | |
| MIBG hemisulfate | MIBG hemisulfate is a radiopharmaceutical used in a scintigraphy method called MIBG scan. It demethylates and oxidizes membrane-associated DNA for the treatment of certain kinds of cancer of the adrenal glands. Uses: Antitumor agent. Synonyms: Iobenguane sulfate; M-Iodobenzylguanidine hemisulfate; 3-Iodobenzyl-guanidine hemisulfate; 3-Iodobenzylguanidine hemisulfate; 2-[(3-iodophenyl)methyl]guanidine sulfuric acid. Grades: 99%. CAS No. 87862-25-7. Molecular formula: C16H22I2N6O4S. Mole weight: 648.3. | |
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