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IQ 3. Group: Biochemicals. Grades: Purified. CAS No. 312538-03-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IQ 3
IQ 3 is a selective and specific c-Jun N-terminal kinase 3 (JNK3) inhibitor with Kd value of 66 nM. It inhibits TNF-α and IL-6 production in vitro and inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells. Synonyms: IQ3; IQ-3; IQ 3; 11H-Indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime. Grades: ≥98% by HPLC. CAS No. 312538-03-7. Molecular formula: C20H11N3O3. Mole weight: 341.32.
2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline-[2-13C] (IQ-2-13C). Group: Biochemicals. Alternative Names: IQ-2-13C. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline (IQ)
IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates. Group: Biochemicals. Alternative Names: IQ. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Exhibits an extraordinarily high mutagenic potency in the Ames test. Group: Biochemicals. Alternative Names: IQx; 3-Methyl-3H-imidazo[4,5-f]quinoxalin-2-amine; 2-Amino-3-Methylimidazo[4,5-f]quinoxaline. Grades: Highly Purified. CAS No. 108354-47-8. Pack Sizes: 2.5mg. Molecular Formula: C??H?N?, Molecular Weight: 199.21. US Biological Life Sciences.
2-Hydroxy derivative of the mutagenic heterocyclic amine, IQ. Group: Biochemicals. Alternative Names: N-OH-IQ. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
IQ-type carcinogens found in cooked food are biotransformed and bind to DNA through sequential N2-hydroxylation and. Group: Biochemicals. Alternative Names: NO2-MeIQx. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
3-Methyl-2-nitro-3H-imidazo[4,5-F]quinoline (Nitro-IQ). Group: Biochemicals. Alternative Names: Nitro-IQ. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7
The Casein Kinase II Inhibitor IV, also referenced under CAS 391670-48-7, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
Cell-permeable. Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β- cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency. Group: Biochemicals. Alternative Names: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide. Grades: Highly Purified. CAS No. 331001-62-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
IQ-3
IQ-3 is a specific inhibitor of the c-Jun N-terminal kinase (JNK) family, with preference for JNK3. IQ-3 exhibits K d values of 0.24 μM, 0.29 μM and 0.066 μM for JNK1, JNK2 and JNK3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312538-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107600.
A closely related isomer to the heterocyclic food mutagen IQ. Useful for biological and structure-activity studies of IQ. Group: Biochemicals. Alternative Names: 3-Methyl-3H-imidazo[4,5-f]isoquinolin-2-amine Hydrobromide. Grades: Highly Purified. CAS No. 1246819-52-2. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline. Group: Biochemicals. Alternative Names: 3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine; IQ. Grades: Highly Purified. CAS No. 76180-96-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H10N4. US Biological Life Sciences.
IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates. Group: Biochemicals. Alternative Names: 3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine-2-13C; IQ-2-13C Dihydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
2-Aminoimidazo[4,5-f]quinoline
A metabolite of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). Group: Biochemicals. Alternative Names: 1H-Imidazo[4,5-f]quinolin-2-amine; 2-Amino-3H-imidazo[4,5-f]quinoline. Grades: Highly Purified. CAS No. 76180-97-7. Pack Sizes: 10mg. US Biological Life Sciences.
4-(4-Chlorophenyl)thiomorpholine 1,1-dioxide. Group: other glass and ceramic materials. Alternative Names: 4-(4-CHLOROPHENYL)THIOMORPHOLINE 1,1-DIOXIDE; 4-(1,1-DIOXOTHIOMORPHOLINO)PHENYL CHLORIDE; CHEMPACIFIC 36177. CAS No. 82222-74-0. Product ID: 4-(4-chlorophenyl)-1,4-thiazinane 1,1-dioxide. Molecular formula: 245.73. Mole weight: C10< / sub>H12< / sub>ClNO2< / sub>S. C1CS(=O)(=O)CCN1C2=CC=C(C=C2)Cl. IQIXFXLKPNFQGQ-UHFFFAOYSA-N. 96%.
(4-Dimethylaminophenyl)di-tert-butylphosphine
(4-Dimethylaminophenyl)di-tert-butylphosphine. Uses: Ligand used in a highly-active palladium precatalyst for the efficient amination of aryl chloride. ligand used in the palladium-catalyzed annulations under microwave enhanced conditions. Group: Organic light-emitting diode (oled) materials. Alternative Names: ZINC34638584; IQTHEAQKKVAXGV-UHFFFAOYSA-N; DTXSID10471005; KS-000005K1; AX8243611; 4-(di-t-butylphosphino)-N,N-dimethylaniline; APhos, 95%; (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine; AKOS016012292; BIS(TERT-BUTYL)4-DIMETHYLAMINOPHENYLPHOSPHINE. CAS No. 932710-63-9. Product ID: 4-ditert-butylphosphanyl-N,N-dimethylaniline. Molecular formula: 265.381g/mol. Mole weight: C16H28NP. CC (C) (C)P (C1=CC=C (C=C1)N (C)C)C (C) (C)C. InChI=1S/C16H28NP/c1-15 (2, 3)18 (16 (4, 5)6)14-11-9-13 (10-12-14)17 (7)8/h9-12H, 1-8H3. IQTHEAQKKVAXGV-UHFFFAOYSA-N.
4-Methylphenyl b-D-thiogalactopyranoside
4-Methylphenyl β-D-thiogalactopyranoside is a synthetic compound acting as a substrate for the enzyme β-D-galactosidase and can be used to induce gene expression in studies related to the lac operon. This compound is particularly useful in molecular biology research for investigating the regulation of gene expression and analyzing protein interactions. Synonyms: 4-METHYLPHENYLTHIO-BETA-D-GALACTOPYRANOSIDE; CHEMBL4064722; (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(p-tolylthio)tetrahydro-2H-pyran-3,4,5-triol; (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyloxane-3,4,5-triol; 4-Methylphenyl 1-thio-b-D-galactopyranoside; SCHEMBL3824089; IQCLIQLFPVKINX-SJHCENCUSA-N; BDBM50247500; 4-Methylphenylthio-?-D-galactopyranoside; 4-Methylphenylthio-b-D-galactopyranoside; WS-02057; CS-0113028; 4-Methylphenylthio- beta -D-galactopyranoside; D77177; p-Methylphenyl 1-thio-beta-D-galactopyranoside; p-Methylphenyl 1 -thio-beta-D-galactopyranoside; W-202184. CAS No. 28244-98-6. Molecular formula: C13H18O5S. Mole weight: 286.35.
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide; (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide; Bromo-Afatinib; C22H19BrClFN4O3; AFATINIB IMPURITY O; SCHEMBL16398947; SCHEMBL16398952; IQJWAIKYBNTYPG-YUKKFKLSSA-N; CS-0164267; (2E)-4-Bromo-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: ≥95%. Molecular formula: C18H15FN4O4. Mole weight: 370.34.
Aniracetam
Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO 2 -induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-5057. CAS No. 72432-10-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-10932.
IQ 1
IQ 1. Group: Biochemicals. Grades: Purified. CAS No. 331001-62-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IQ 1
IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin -driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP -mediated transcription and preventing conversion to β-catenin/p300 -mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331001-62-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10593.
IQ-1
IQ-1, a cell-permeable tetrahydroisoquinolinylidene compound, disrupts Wnt signaling that enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Synonyms: 2-(4-Acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide. Grades: >98%. CAS No. 331001-62-8. Molecular formula: C21H22N4O2. Mole weight: 362.42.
IQ-1S free acid
IQ-1S free acid is a potent, selective c-Jun N-Terminal Kinase inhibitor with a preference for JNK3 (IC50=390, 360 and 87 nM for JNK1, 2 and 3 respectively). In vivo IQ-1S free acid exhibits immunosuppressant property and it inhibits murine delayed-type h. Synonyms: 11-nitroso-10H-indeno[1,2-b]quinoxaline IQ-1S (free acid) CHEMBL3393601 11-(hydroxyimino)indeno[2,3-b]quinoxaline 11-nitroso-10H-indeno[1,2-b]quinoxaline. CAS No. 23146-22-7. Molecular formula: C15H9N3O. Mole weight: 247.25.
Isoleucyl-glutamine
Isoleucyl-glutamine is a dipeptide composed of isoleucine and glutamine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-IQ-OH; L-isoleucyl-L-glutamine; Ile-Gln; L-Ile-L-Gln; L-Glutamine, L-isoleucyl-; (S)-5-amino-2-((2S,3S)-2-amino-3-methylpentanamido)-5-oxopentanoic acid. Grades: ≥95%. CAS No. 59652-60-7. Molecular formula: C11H21N3O4. Mole weight: 259.30.
A cell-permeable indenoquinoxalinone-oxime (IQ) compound that acts as a potent, non-toxic, reversible, ATP-competitive, high-affinity inhibitor of JNK (=390, 360 and 87nM for JNK1, JNK2 and JNK3, respectively) with moderate selectivity over CK1d, PI 3-Ky, and MKNK2 (IC50=1.4, 1.2, and 1.8uM, respectively). Shown to reduce c-Jun-Ser63 phosphorylation, and block the production of LPS-induced TNF-a (IC50 = 250nM) and IL-6 (IC50=610nM) in MonoMac-6 monocytic cells and in human hPBMCs, respectively. Also shown to inhibit NF-kB/AP-1 reporter activity (IC50=1.8uM) in human THP1-Blue monocytic cells and diminish nitric oxide production in murine J774-A.1 macrophages (IC50=12.5uM). Exhibits favorable pharmacokinetics properties and efficiently reduces ovalbumin-induced CD+ T-cell immune inflammation in a murine delayed-type hypersensitivity model (12.5mg/kg, two per day dosage, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H?N?Ona, Primary Target: JNK1,2,3. US Biological Life Sciences.
Levofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class[1][2] and is used to treat severe or life-threatening bacterial infections or bacterial infections that have failed to respond to other antibiotic classes.[3][4] It is sold under various brand names, such as Levaquin and Tavanic, the most common. In form of ophthalmic solutions it is known as Oftaquix, Quixin and Iquix. Group: Biochemicals. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, Hemihydrate. Grades: Highly Purified. CAS No. 138199-71-0. Pack Sizes: 100mg. US Biological Life Sciences.
MeIQx, also known as 8-Methyl-IQX, is a synthetic, pale orange to brown crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Methyl-IQX; MeIQx. Product Category: Others. Appearance: Solid powder. CAS No. 77500-04-0. Molecular formula: C11H11N5. Mole weight: 213.24. Purity: >98%. IUPACName: 3,8-Dimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine. Canonical SMILES: NC1=NC2=C3N=C(C)C=NC3=CC=C2N1C. Product ID: ACM77500040. Alfa Chemistry ISO 9001:2015 Certified. Categories: MeiQ: Labyrinth of Death.
mPEG7-NH2
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and redu. Group: Poly(ethylene glycol) and poly(ethylene oxide). Product ID: 2- [2- [2- [2- [2- [2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanamine. Molecular formula: 339.42g/mol. Mole weight: C15H33NO7. COCCOCCOCCOCCOCCOCCOCCN. InChI= 1S / C15H33NO7 / c1-17-4-5-19-8-9-21-12-13-23-15-14-22 -11-10-20-7-6-18-3-2-16 / h2-16H2, 1H3. IQQSLHPGFFGOJW-UHFFFAOYSA-N.
Palatinose Monohydrate
Palatinose Hydrate, a natural occurring disaccharide composed of α-1,6-linked glucose and fructose, can be used as an alternative sugar. Because it is absorbed more slowly than sucrose, it can be used as a sweetener for diabetic patients. Synonyms: 6-O-α-D-Glucopyranosyl-D-fructose Monohydrate; Galen IQ Hydrate; Palatinose Monohydrate; Isomaltulose Monohydrate; Palatinose IC Monohydrate; Palatinose ICP Monohydrate. CAS No. 58024-13-8. Molecular formula: C12H22O11 H2O. Mole weight: 342.30.
rac 1-Phenyl-1,2,3,4-tetrahydroisoquinoline
1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin intermediate. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline had been detected in parkinsonian human brain. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline maybe a candidate for endogenous MPTP-like neurotoxin since it is a structural analogue of MPTP which produces parkinsonism in humans. Group: Biochemicals. Alternative Names: (±) -1-Phenyl-1, 2, 3, 4-tetra hydroisoquinoline; (±)-IQL; 1,2,3,4-Tetrahydro-1-phenylisoquinoline; NSC 338399. Grades: Highly Purified. CAS No. 22990-19-8. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Sodium ammonium hydrogen phosphate tetrahydrate
Sodium ammonium hydrogen phosphate tetrahydrate. Group: Electrolytes. Alternative Names: Ammonium sodium phosphate. CAS No. 7783-13-3. Product ID: Azanium; sodium; hydrogen phosphate; tetrahydrate. Molecular formula: 209.07. Mole weight: H13NNaO8P. [NH4+]. O. O. O. O. OP(=O)([O-])[O-]. [Na+]. InChI=1S/H3N.Na.H3O4P.4H2O/c;1-5(2, 3)4;/h1H3;(H3, 1, 2, 3, 4);4*1H2/q;+1;/p-1. IQTQISLCLWJRPM-UHFFFAOYSA-M. 99%+.
(S)-(-)-Pantoprazole
An impurity of Pantoprazole which is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). Synonyms: (-)-Pantoprazole; Zosecta; L-Pantoprazole; 142678-35-1; S-(-)-Pantoprazole; S-Pantoprazole; SX78SGO2TV; Pantoprazole, S-; UNII-SX78SGO2TV; 1H-Benzimidazole, 6-(difluoromethoxy)-2-((S)-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-; 6-(difluoromethoxy)-2-[(S)-(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole; (S)-(-)-Pantoprazole; PANTOPRAZOLE, (S)-; SCHEMBL29466; CHEMBL3526697; S-PANTOPRAZOLE [WHO-DD]; IQPSEEYGBUAQFF-SANMLTNESA-N; DTXSID201015709; PD119113; Q27289440. Grades: > 95%. CAS No. 142678-35-1. Molecular formula: C16H15F2N3O4S. Mole weight: 383.38.
2-Amino-3-methyl-3H-imidazo[4,5-F]isoquinoline
A closely related isomer to the heterocyclic food mutagen IQ. Useful for biological and structure-activity studies of IQ. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2-Amino-3-methyl-3H-imidazo[4,5-H]isoquinoline
A closely related isomer to the heterocyclic food mutagen IQ. Useful for biological and structure-activity studies of IQ. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2-Amino-3-methyl-3H-imidazo[4,5-H]quinoline
A closely related isomer to the heterocyclic food mutagen IQ. Useful for biological and structure-activity studies of IQ. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
The JNK Inhibitor XV, IQ-1S controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
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