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| Product | Description | |
|---|---|---|
| IQ-1 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| IQ-1 | IQ-1, a cell-permeable tetrahydroisoquinolinylidene compound, disrupts Wnt signaling that enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Synonyms: 2-(4-Acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide. Grades: >98%. CAS No. 331001-62-8. Molecular formula: C21H22N4O2. Mole weight: 362.42. |  |
| IQ-1 (2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide) | Cell-permeable. Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β- cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency. Group: Biochemicals. Alternative Names: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide. Grades: Highly Purified. CAS No. 331001-62-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| IQ 1 | IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin -driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP -mediated transcription and preventing conversion to β-catenin/p300 -mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331001-62-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10593. |  |
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