irl-1620 Suppliers USA

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IRL-1620 IRL-1620, also known as SPI-1620, is an endothelin B receptor agonist. SPI-1620 is a highly selective peptide agonist of the endothelin-B receptor. Endothelin B receptor agonist SPI-1620 binds to endothelin-B receptors on endothelial cells in tumor blood vessels, which, unlike the angioarchitecture of normal blood vessels, are relatively devoid of smooth muscle. This agent may induce a transient, selective increase in blood flow to a tumor, which may result in an increase in the delivery of anticancer agents to the tumor and, so, an increase in anticancer agent efficacy. Synonyms: SPI-1620; IRL1620; IRL 1620. CAS No. 142569-99-1. Molecular formula: C86H117N17O27. Mole weight: 1820.97. BOC Sciences 11
IRL-1620 IRL-1620. Group: Biochemicals. Grades: Purified. CAS No. 142569-99-1. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 5
Worldwide
A-192621 A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Synonyms: (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propoxyphenyl)pyrrolidine-3-carboxylic acid; (2R-(2alpha,3beta,4alpha)-4-(1,3-benzodioxol-5-yl)-1-(2-(2,6-diethylphenyl)amino)-2-oxoethyl)-2-(4-propoxyphenyl)-3-pyrrolidinecarboxylic acid; A 192621; A-192621; A192621. Grades: >98%. CAS No. 195529-54-5. Molecular formula: C33H38N2O6. Mole weight: 558.675. BOC Sciences

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