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| Product | Description | |
|---|---|---|
| Ischemin sodium salt | Ischemin sodium salt. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Ischemin sodium salt | Ischemin sodium salt is the sodium form of ischemin, which is a potent CBP bromodomain inhibitor. It inhibits p53 interaction with CBP and alters post-translational modifications on p53 and histones. It decreases p53 transcriptional activity in cells. It protects against doxorubicin-induced apoptosis in ischemic cardiomyocytes in vitro. It is cell permeable. Synonyms: 5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt. Grades: ≥99% by HPLC. Molecular formula: C15H16N3O4SNa. Mole weight: 357.36. |  |
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