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| Product | Description | |
|---|---|---|
| ISCK03 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| ISCK03 | ISCK03, a phenyl-imidazolosulfonamide compound, is a cell-permeable, specific SCF/c-Kit inhibitor (IC50 <<2.5 μM in cell-free kinase assays). Synonyms: 4-tert-butyl-N-(4-imidazol-1-ylphenyl)benzenesulfonamide; c-Kit Inhibitor II; Stem-Cell Factor/c-Kit Inhibitor; ISCK-03; ISCK 03. CAS No. 945526-43-2. Molecular formula: C19H21N3O2S. Mole weight: 355.45. |  |
| ISCK03 | ISCK03 is a potent c-kit inhibitor. ISCK03 inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. ISCK03 also inhibited p44/42 ERK mitogen-activated protein kinase (MAPK) phosphorylation, which is known to be involved in SCF/c-kit downstream signaling. ISCK03 might be used as skin-whitening agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ISCK03, ISCK-03, ISCK 03. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 945526-43-2. Molecular formula: C19H21N3O2S. Mole weight: 355.46. Purity: >98%. IUPACName: [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide. Canonical SMILES: O=S(N(C1=CC=C(C(C)(C)C)C=C1)C2=CC=C(N3C=CN=C3)C=C2)=O. Product ID: ACM945526432-2. Alfa Chemistry ISO 9001:2015 Certified. |  |
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