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Isofagomine, an imino pyranose compound, has been found to be a glucosylceramidase stimulant and could exhibit activity in Gaucher's disease. Synonyms: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol; Isofagomine; Iso-Fagomine. Grades: 98%. CAS No. 169105-89-9. Molecular formula: C6H13NO3. Mole weight: 147.17.
Isofagomine D-Tartrate
The D-Tartrate salt form of Isofagomine, an imino pyranose compound, has been found to be a glucosylceramidase stimulant and could exhibit activity in Gaucher's disease. Synonyms: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol (2S,3S)-2,3-dihydroxysuccinate; AT2101; AT-2101, AT 2101; Isofagomine D-Tartrate; Isofagomine; Afegostat; D-Isofagomine; isoFagomine brand name: Plicera. Grades: 98%. CAS No. 957230-65-8. Molecular formula: C10H19NO9. Mole weight: 297.26.
Isofagomine hydrochloride
Isofagomine hydrochloride is a vital compound widely used in the biomedical industry for the research of lysosomal storage diseases such as Gaucher's disease. This product acts as an inhibitor of the enzyme glucosylceramide synthase, which helps in reducing the accumulation of harmful lipids in the lysosomes. Synonyms: (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol; 5-Hydroxymethyl-3,4-piperidinediol; Afegostat. CAS No. 161302-93-8. Molecular formula: C6H13NO3 HCl. Mole weight: 183.63.
5-epi-isofagomine
5-epi-isofagomine, a highly potent and selective inhibitor, has garnered substantial attention in the biomedical realm due to its remarkable efficacy against Gaucher disease. This scientific marvel operates by skillfully impeding the glucocerebrosidase enzyme, ensuring an impediment in the accumulation of glucocerebroside within cells. Synonyms: 5-epi-(3R,4R,5R)-5-(hydroxymethyl)-3,4-piperidinediol (3R,4R,5S)-5-(Hydroxymethyl)-3,4-piperidinediol. CAS No. 202979-51-9. Molecular formula: C6H13NO3. Mole weight: 147.17.
A selective and very strong inhibitor of ß-Glucosidase (Ki0.11uM). Group: Biochemicals. Alternative Names: 5-epi-(3R,4R,5R)-5-(Hydroxymethyl)-3,4-piperidinediol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Intermediate in the production of Isofagomine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1084896-52-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Afegostat
Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine; Isofagomine. CAS No. 169105-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14829.
Afegostat D-Tartrate
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E.
An intermediate in the production of Isofagomine. Uses: Intermediate in the production of isofagomine. Synonyms: Phenylmethyl 4-Cyano-4-deoxy-2,3-O-[(1S,2S)-1,2-dimethoxy-1,2-dimethyl-1,2-ethanediyl]-β-D-arabinopyranoside. Grades: 95%. CAS No. 1084896-40-1. Molecular formula: C19H25NO6. Mole weight: 363.4.
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