Isomerase Suppliers USA
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Product | Description | |
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Peptidylprolyl Isomerase F (PPIF) Recombinant, Mouse, Unstained Protein Molecular Weight Marker Quick inquiry Where to buy Suppliers range | Peptidylprolyl Isomerase F (PPIF) Recombinant, Mouse, Unstained Protein Molecular Weight Marker. Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
Triosephosphate isomerase 1 (23-37) Quick inquiry Where to buy Suppliers range | Triosephosphate isomerase 1 (23-37) is a fragment of TPI1. Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. Synonyms: Triose-phosphate isomerase (23-37); Methylglyoxal synthase (23-37). | |
Triosephosphate isomerase 1 (23-37) Quick inquiry Where to buy Suppliers range | Triosephosphate isomerase. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-032. | |
3-?(4-?Methoxyphenyl)?-?5-?[(5-?nitro-?2-?thienyl)?methylene]?-?2-?thioxo-4-?thiazolidinone Quick inquiry Where to buy Suppliers range | 3-?(4-?Methoxyphenyl)?-?5-?[(5-?nitro-?2-?thienyl)?methylene]?-?2-?thioxo-4-?thiazolidinone is a protein disulfide isomerases (PDI) inhibitor. PDIs are involved with protein folding in the endoplasmic reticulum. PDI inhibitors are potential anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 346640-08-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H10N2O4S3, Molecular Weight: 378.45. US Biological Life Sciences. | Worldwide |
7-O-(Triethylsilyl)-2-O-Tert-Butyl(Dimethyl)Silyl-Iscephalomannine Quick inquiry Where to buy Suppliers range | 7-O-(Triethylsilyl)-2-O-Tert-Butyl(Dimethyl)Silyl-Iscephalomannine. Group: Organosilicone. Alternative Names: Description: Applications7-O- (tri ethyl sily l ) -2-O-Tert-Butyl (Di methyl ) Sily l -IsCEphalomannineisanintermediateused inthesynthesisofisCEphalomannine (I7 89500) , Whichisacephalomannine (C25 8500) Isomerasanimpurityinpaclitaxel (P132500) Activepharmaceuticalingre dient. Paclitaxelimpuritya. Itbindst othen-Terminal31Amiacidsofthebeta-Tubulinsubunitinthemicrotubule, Rath erthantotubulindimers. Paclitaxel-Impuritya. Referenceskerns, E. , Eta l. Druginfoj. , 32, 471 (1998) , D arrington, R. , Etal. J. Pharm. Sc i. , 93, 838 (2004) . Product ID: ACMA00021821. Molecular formula: C57H81NO14Si2. Mole weight: 1060.42 g/mol. | |
a-D-Mannose-1-phosphate ammonium salt Quick inquiry Where to buy Suppliers range | a-D-Mannose-1-phosphate ammonium salt is a remarkable compound, used for studying metabolic disorders like mannose phosphate isomerase deficiency. Furthermore, substantiated research points towards its potential role in the development of antiviral compounds, specifically against Dengue virus invasion, owing to its remarkable capacity in obstructing viral entry. Molecular formula: C6H19O9PN2. Mole weight: 294.20. | |
AY 9944 Quick inquiry Where to buy Suppliers range | Cholesterol synthesis inhibitor; inhibits both 7-dehydrocholesterol ?7-reductase and ?8,7-sterol isomerase. A sonic hedgehog inhibitor. Group: Biochemicals. Alternative Names: trans-N1, N4-Bis [ (2-chlorophenyl) methyl ] -1, 4-cyclohexane dimethanamine Hydrochloride; N, N'-Bis (o-chlorobenzyl)-trans-1, 4-cyclohexanebis (methylamine) Dihydrochloride. Grades: Highly Purified. CAS No. 366-93-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bacitracin F Quick inquiry Where to buy Suppliers range | Bacitracin F is a major Bacitracin analog, a peptide antibiotic used as an inhibitor of protein disulfide isomerase (PDI). It is isolated from Bacillus. Synonyms: Bacitracin H3; N2-[N-[[2-[(S)-2-Methylbutanoyl]thiazol-4-yl]carbonyl]-L-Leu-D-Glu-L-Ile-]cyclo(L-Lys-D-Orn-L-Ile-D-Phe-L-His-D-Asp-L-Asn-). Grades: >95%. CAS No. 22601-63-4. Molecular formula: C66H98N16O17S. Mole weight: 1419.68. | |
CCF-642 Quick inquiry Where to buy Suppliers range | CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable to the first-line multiple myeloma therapeutic bortezomib. Synonyms: 3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone; CCF-642; CCF 642; CCF642. CAS No. 346640-08-2. Molecular formula: C15H10N2O4S3. Mole weight: 378.44. | |
DL-Arabinose Quick inquiry Where to buy Suppliers range | DL-Arabinose is a fundamental constituent found abundantly in nature. Serving as an indispensable component in the creation of Xylose isomerase is an enzymatic catalyst facilitating the transformation of xylose into xylulose, it assumes a paramount role in studying diverse metabolic anomalies like diabetes and obesity. Synonyms: Arabinose; (±)-Arabinose; dl-Arabinose. Grades: ≥95%. CAS No. 147-81-9. Molecular formula: C5H10O5. Mole weight: 150.13. | |
D-Mannose-6-phosphate disodium salt hydrate Quick inquiry Where to buy Suppliers range | D-Mannose-6-phosphate disodium salt hydrate, an indispensable compound within the biomedical sector, holds immense significance in addressing and overseeing a myriad of conditions such as diabetes, urinary tract infections, and glycogen storage diseases. Its pharmaceutical formulations benefit from the heightened stability and solubility imparted by this particular salt hydrate manifestation. Uses: Mannose-6-phosphate (m6p) is a molecule bound by lectin in the immune system. m6p is converted to fructose 6-phosphate by mannose phosphate isomerase. m6p is a key targeting signal for acid hydrolase precursor proteins that are destined for transport to lysosomes. Synonyms: Disodium D-mannose 6-phosphate;Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate; D-Mannose 6-phosphate disodium salt;mannose-6-phosphate disodium; d-Mannose, 6-(dihydrogen phosphate), disodium salt. CAS No. 33068-18-7. Molecular formula: C6H11O9PNa2 H2O. Mole weight: 322.11. | |
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA Quick inquiry Where to buy Suppliers range | H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is the chromogenic substrate for Pin1, an important and conserved mitotic peptidyl-prolyl isomerase (PPIase) that specifically recognizes the phosphoserine-proline bonds present in mitotic phosphoproteins (kcat/Km = 20160 mM-1s-1). Synonyms: L-Argininamide, L-tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-; L-Tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-L-argininamide; WFY(p)SPR-pNA. CAS No. 202739-41-1. Molecular formula: C49H59N12O13P. Mole weight: 1055.05. | |
L-Arabinose Quick inquiry Where to buy Suppliers range | L(+)-Arabinose is a pentose monosaccharide whose transcription is regulated by Ara-C proteins and is a substrate for L-arabinose dehydrogenase, galactose dehydrogenase. It is not fermented by yeast. Used as a one-way or reversible switch for protein expression. It is also used to make arabinosyl nucleosides. L-Arabinose is used as a substrate to identify, differentiate and characterize pentose sugar isomerase(s). L-Arabinose is used in the bioproduction of L-ribose. L-Arabinose is the naturally occurring isomer and is a constituent of plant polysaccharides. Most bacteria contain an inducible arabinose operon that codes for a series of enzymes and transporters that allows L-arabinose to be used as the sole carbon source in microbial culture. Group: Biochemicals. Alternative Names: Beta-L-Arabinopyranose; Beta-L-(+)-ARABINOSE; L-(+)-Arabinose; Pectinose; Arabitol, L-(-)-(RG); L-Arabinopyranose; (2R,3R,4S,5S)-oxane-2,3,4,5-tetrol. Grades: Reagent Grade. CAS No. 87-72-9. Pack Sizes: 100g, 500g, 1Kg, 2.5Kg. Molecular Formula:?C5H10O5 , Molecular Weight:?150.13. US Biological Life Sciences. | Worldwide |
LOC14 Quick inquiry Where to buy Suppliers range | LOC14 is a protein disulfide isomerase modulator with Kd value of 62 nM. It can force protein disulfide isomerase to adopt an oxidized conformation and suppress its activity. Synonyms: LOC14; LOC-14; LOC 14. 2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 877963-94-5. Molecular formula: C16H19N3O2S. Mole weight: 317.41. | |
MitoBloCK-6 (2- ( ( (4-Anilinophenyl) imino) methyl) -4, 6-dichlorophenol, 2, 4-Dichloro-6- ( ( ( ( (phenylamino) phenyl) imino) methyl) phenol) , Mitochondrial Protein Import Blocker from the Carla Koehler Laboratory, MB6, MB-6) Quick inquiry Where to buy Suppliers range | A cell-permeable, stable dichlorosalicylalde hyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700nM, 900nM, and 1.4uM for ALR, Erv1, and Erv2, respectively). Significantly reduces the import of CX9 proteins, Erv1, Tim23, and ADP/ATP carrier (AAC). However, it does not affect mitochondrial membrane integrity as evidenced by the lack of aconitase, AAC, Tim54, Mia40, and cytochrome c release. Has no effect on protein disulfide isomerase, flavin adenine dinucleotide, and succinate dehydrogenase activities and does not disrupt mitochondrial net work or reduce viability of cells even at high concentrations (~100uM in HeLa and HEK293 cells). Reported to specifically cause cytochrome c release, activate caspase-3, and induce apoptosis in human embryonic stem cells (~20uM), but not in differentiated cells. Reversibly impairs cardiac development and reduces heart rate in zebra fish that is attributed to mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??Cl?N?O, Primary Target: Erv1. US Biological Life Sciences. | Worldwide |
P1 Quick inquiry Where to buy Suppliers range | A protein disulfide isomerase inhibitor with IC50 value of 1.7 μM. It can inhibit the proliferation of numerous cancer cell lines. Synonyms: PDI-IN-P1; PDI IN P1; PDIINP1; PDI inhibitor P1; PDI-inhibitor-P1; N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide. Grades: ≥98% by HPLC. CAS No. 1461648-55-4. Molecular formula: C30H37N3O7S. Mole weight: 583.7. | |
P1 (N-[ (1, 1-Dimethylethoxy) carbonyl]-L-phenylalanyl-O- (ethenylsulfonyl) -N-4-pentyn-1-yl-L-tyrosinamide) Quick inquiry Where to buy Suppliers range | Protein disulfide isomerase (PDI) inhibitor (IC50 = 1.7uM). Inhibits proliferation of numerous cancer cell lines. Cell permeable. Group: Biochemicals. Grades: Highly Purified. CAS No. 1461648-55-4. Pack Sizes: 1mg. Molecular Formula: C30H37N3O7S, Molecular Weight: 583.7. US Biological Life Sciences. | Worldwide |
PACMA 31 Quick inquiry Where to buy Suppliers range | PACMA 31 is a protein disulfide isomerase family inhibitor as promising target for chemotherapy. It inhibits growth of ovarian cancer cells. Synonyms: PACMA 31; PACMA31; PACMA-31; N-(2,4-Dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycylglycine ethyl ester. Grades: ≥99% by HPLC. CAS No. 1401089-31-3. Molecular formula: C21H22N2O6S. Mole weight: 430.47. | |
Suc-Ala-Glu-Pro-Phe-pNA Quick inquiry Where to buy Suppliers range | Suc-AEPF-pNA can be used as a chromogenic substrate for the peptidylprolyl isomerase Pin1. Synonyms: Suc-AEPF-pNA. Grades: ≥ 99%. CAS No. 128802-76-6. Molecular formula: C32H38N6O11. Mole weight: 682.69. | |
Suc-Ala-Phe-Pro-Phe-pNA Quick inquiry Where to buy Suppliers range | Suc-Ala-Phe-Pro-Phe-pNA is a substrate for FK-506 binding proteins and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). Synonyms: Suc-apppa; Succinimidyl-alanyl-phenylalanyl-prolyl-phenylalanine 4-nitroanilide. Grades: >99%. CAS No. 128802-73-3. Molecular formula: C36H40N6O9. Mole weight: 700.75. | |
Tacrolimus Quick inquiry Where to buy Suppliers range | FK-506 is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Uses: Drug. Synonyms: Prograf; Fujimycin; FK506; Protopy. Grades: >98%. CAS No. 104987-11-3. Molecular formula: C44H69NO12. Mole weight: 804.02. |