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| Product | Description | |
|---|---|---|
| ITX-5061 | ITX-5061 is a scavenger receptor B1 antagonist. Preclinical studies show that ITX-5061 is a selective inhibitor of HCV entry into hepatocytes. It can prevent virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA were on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide;1252679-52-9 (HCl salt). Grades: 98%. CAS No. 848144-15-0. Molecular formula: C30H37N3O7S. Mole weight: 583.70. |  |
| ITX-5061 HCl | This active molecular is a scavenger receptor B1 antagonist under the development by iTherX Pharmaceuticals for the treatment of Hepatitis C. ITX-5061 shows a special mechanism of action that prevents the hepatitis C virus from entering liver cells. Preclinical studies have shown that ITX-5061 can prevent virus binding/fusion and cell to cell spread. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA was on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; UNII-J4RA8K2Q2A; J4RA8K2Q2A;CHEMBL3402567;N-[5-tert-butyl-3-(methanesulfonamido)-2-methoxyphenyl]-2-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-2-oxoacetamide;hydrochloride;848144-15-0 (free base). Grades: 98%. CAS No. 1252679-52-9. Molecular formula: C30H38ClN3O7S. Mole weight: 620.16. | |
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