Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| IWP 12 | IWP 12. Group: Biochemicals. Grades: Purified. CAS No. 688353-45-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| IWP 12 | IWP 12 is a Wnt inhibitor that prevents palmitylation of Wnt proteins by Porcupine (Porcn). It blocks post resection juvenile zebrafish tailfin regeneration and is suitable for in vivo assays. It is a membrane-bound O-acyltransferase (MBOAT) and activates Wnt proteins with IC50 value of 15 nM. It inhibits Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. Synonyms: IWP12; IWP 12; IWP-12; N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]acetamide. Grades: ≥98% by HPLC. CAS No. 688353-45-9. Molecular formula: C18H18N4O2S3. Mole weight: 418.56. |  |
| 2,3,6-Trifluorophenylboronic acid | 2,3,6-Trifluorophenylboronic acid. Group: Salt. Alternative Names: RARECHEM AH PB 0123; RARECHEM AH PB 0119; 2,3,6-Trifluorobenzeneboronic acid; 2,3,6-Trifluorophenylboronic acid; 2,3,6-Trifluorophenylboronic acid. CAS No. 247564-71-2. Product ID: (2,3,6-trifluorophenyl)boronic acid. Molecular formula: 175.9g/mol. Mole weight: C6H4BF3O2. B(C1=C(C=CC(=C1F)F)F)(O)O. InChI=1S/C6H4BF3O2/c8-3-1-2-4 (9)6 (10)5 (3)7 (11)12/h1-2, 11-12H. IWPDDRPLEKURGG-UHFFFAOYSA-N. |  |
| Porcn Inhibitor II, C59 (Wnt-C59, Wnt Pathway Inhibitor XVI, 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide) | A cell-permeable pyridinylphenyl-acetamide that is much more potent than IWP-2 in inhibiting MBOAT family member Porcupine-mediated Wnt palmitoylation (IC50 = 74 pM in STF reporter assays using Wnt3a-transfected HEK293). Shown to be effective against Porcn of murine and human, but not xenopus, species and potently inhibit the processing of both canonical and non-canonical Wnt subtypes. C59 is demonstrated to be orally active and effectively suppress MMTV-WNT1 tumor expansion in mice (5mg/kg & 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1243243-89-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
