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| Product | Description | |
|---|---|---|
| Ixabepilone | Ixabepilone (also known as azaepothilone B, or BMS-247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Ixabepilone was approved in 2007. Synonyms: Azaepothilone B; BMS247550; BMS-247550; BMS 247550; Ixempra. Grades: >98%. CAS No. 219989-84-1. Molecular formula: C27H42N2O5S. Mole weight: 506.7. |  |
| Ixabepilone | Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Group: Inhibitors. Alternative Names: IXABEPILONE;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,9,9-pentamethyl-14-[(E) -1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1.0]heptadecane-8,12-dione;Aza-epothilone B;Bms 247550-1;Ixempra;Ixempra kit;Unii-K27005np0a;Azi-epothilone B. CAS No. 219989-84-1. Molecular formula: C27H42N2O5S. Mole weight: 506.7. Appearance: Solid. Purity: 0.9984. Canonical SMILES: O=C ([C@@H] ([C@H] ([C@H] (CCC[C@]1 (O[C@]1 (C[C@H] (N2)/C (C)=C/C3=CSC (C)=N3)[H])C)C)O)C)C (C) ([C@H] (CC2=O)O)C. Catalog: ACM219989841. |  |
| Ixabepilone | Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-247550; Aza-epothilone B. CAS No. 219989-84-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10222. |  |
| Ixabepilone Impurity 1 | Grades: > 95%. Molecular formula: C27H42N2O5S. Mole weight: 506.71. | |
| Ixabepilone Impurity 2 | an impurity of Ixabepilone. Synonyms: (Z)-Ixabepilone; (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-((Z)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione. Grades: > 95%. CAS No. 1220999-07-4. Molecular formula: C27H42N2O5S. Mole weight: 506.71. | |
| Ixabepilone Impurity 3 | Grades: > 95%. Molecular formula: C27H42N2O5S. Mole weight: 506.71. | |
| Ixabepilone Impurity 4 | Grades: > 95%. Molecular formula: C27H44N2O6S. Mole weight: 524.73. | |
| Ixabepilone Impurity 6 | an impurity of ixabepilone. Synonyms: (4S,7R,8S,9S,13R,14R)-14-((S,E)-2-Amino-3-methyl-4-(2-methylthiazol-4-yl)but-3-en-1-yl)-4,8,13-trihydroxy-5,5,7,9,13-pentamethyloxacyclotetradecane-2,6-dione. Grades: > 95%. CAS No. 1220999-09-6. Molecular formula: C27H44N2O6S. Mole weight: 524.73. | |
| Ixabepilone Impurity 7 | an impurity of ixabepilone. Synonyms: (3S,6R,7S,8S)-11-((2R,3S)-3-((S,E)-2-Azido-3-methyl-4-(2-methylthiazol-4-yl)but-3-en-1-yl)-2-methyloxiran-2-yl)-3,7-dihydroxy-4,4,6,8-tetramethyl-5-oxoundecanoic Acid. Grades: > 95%. Molecular formula: C27H42N4O6S. Mole weight: 550.72. | |
| (1R, 5S, 6S, 7R, 10S, 14S, 16S)-6, 10-Dihydroxy-1, 5, 7, 9, 9-pentamethyl-14-[(E)-1-(2-methyl-1, 3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1. 0]heptadecane-8, 12-dione | (1R, 5S, 6S, 7R, 10S, 14S, 16S)-6, 10-Dihydroxy-1, 5, 7, 9, 9-pentamethyl-14-[(E)-1-(2-methyl-1, 3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1. 0]heptadecane-8, 12-dione. Group: Biochemicals. Alternative Names: Azaepothilone b; Ixabepilone. Grades: Highly Purified. CAS No. 219989-84-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H42N2O5S. US Biological Life Sciences. |  Worldwide |
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