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| Product | Description | |
|---|---|---|
| Ixazomib | Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC 50 of 3.4 nM ( K i of 0.93 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN2238. CAS No. 1072833-77-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10453. |  |
| Ixazomib citrate | Ixazomib citrate (MLN9708) is a selective, orally active, second-generation proteasome inhibitor. Ixazomib citrate can be used for the study of a broad range of human malignancies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN9708. CAS No. 1239908-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10452. | |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Synonyms: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. Grade: 98%. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. |  |
| Ixazomib Impurity 15 | Ixazomib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10203-08-4. Molecular formula: C7H4Cl2O. Mole weight: 175.01. Catalog: APB10203084. |  |
| Ixazomib Impurity 19 | Ixazomib Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. Catalog: APB1239908203. | |
| Ixazomib Impurity 22 | Ixazomib Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10541-71-6. Molecular formula: C7H3Cl5. Mole weight: 264.35. Catalog: APB10541716. | |
| Ixazomib Impurity 9 | Ixazomib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.35. Catalog: APB1092351671. | |
| IXA4 | IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 transiently activates protective IRE1/XBP1s signaling in liver without inducing RIDD or TRAF2/JNK signaling. IXA4 treatment improves systemic glucose metabolism and liver insulin action through IRE1-dependent remodeling of the hepatic transcriptome that reduces glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Our findings indicate that systemic, transient activation of IRE1/XBP1s signaling engenders multi-tissue benefits that integrate to mitigate obesity-driven metabolic dysfunction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXA4; IXA-4; IXA 4. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1185329-96-7. Molecular formula: C24H28N4O4. Mole weight: 436.51. Purity: >98%. IUPACName: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide. Canonical SMILES: CC1=CC=C(OCCN(C(CN2N=CC(NC(=O)CCOC3=CC=CC=C3)=C2)=O)C)C=C1. Product ID: ACM1185329967. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ixazomib. |  |
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