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J 104129 fumarate The fumarate salt form of J 104129, which has been found to be a muscarinic M3 receptor antagonist with high selectivity. Synonyms: J-104129 fumarate; J 104129 fumarate; J104129 fumarate; (αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-pentenyl)-4-piperidinyl]benzeneacetamide fumarate. Grades: ≥99% by HPLC. CAS No. 257603-40-0. Molecular formula: C24H36N2O2.C4H4O4. Mole weight: 500.63. BOC Sciences 10
J 104129 Fumarate Potent M3 muscarinic receptor antagonist that displays ~ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490nM for human M3, M1 and M2 receptors respectively). Exhibits >250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively). Group: Biochemicals. Alternative Names: (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide Fumarate; (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide (2E)-2-Butenedioate (1:1) (salt) (9CI). Grades: Highly Purified. CAS No. 257603-40-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?; (C?H?O?), Molecular Weight: 500.63. US Biological Life Sciences. USBiological 5
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