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JC-1 JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=488 nm, Em=595 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=488 nm, em= 530 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: CBIC2. CAS No. 3520-43-2. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15534. MedChemExpress MCE
JC-1 JC-1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBIC2(3). Product Category: Other Fluorophores. Appearance: Dark violet powder. CAS No. 3520-43-2. Molecular formula: C25H27Cl4IN4. Mole weight: 652.23. Purity: 95%+. IUPACName: 5,6-dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl)prop-2-enylidene]-1,3-diethylbenzimidazole;iodide. Canonical SMILES: CCN1C2=CC(=C(C=C2[N+](=C1/C=C/C=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-]. Product ID: ACM3520432-1. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide, JC-130B Hercules. Alfa Chemistry. 2
JC-1 solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
JC-1 The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590nm) in healthy cells. After cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio. Group: Biochemicals. Alternative Names: 5, 5', 6, 6'-Tetrachloro-1, 1', 3, 3'-tetraethyl benzimidazolyl carbocyanine iodide. Grades: Highly Purified. CAS No. 3520-43-2, 47729-63-5. Pack Sizes: 1mg, 5x1mg. Molecular Formula: C25H27Cl4IN4. US Biological Life Sciences. USBiological 3
Worldwide
JC-1 - CAS 47729-63-5 A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential ??m in cells, tissues, and isolated mitochondria. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products

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