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| Product | Description | |
|---|---|---|
| JNJ-37822681 dihydrochloride | JNJ-37822681 dihydrochloride is a potent, specific, centrally active and fast-dissociating antagonist of dopamine D2 receptor with a moderate binding affinity to dopamine D2L receptor (Ki = 158 nM). It has the potential to treat schizophrenia and bipolar disorder. Synonyms: 3-Pyridazinamine, N-(1-((3,4-difluorophenyl)methyl)-4-piperidinyl)-6-(trifluoromethyl)-, hydrochloride (1:2); N-(1-(3,4-difluorobenzyl)piperidin-4-yl)-6-(trifluoromethyl)pyridazin-3-amine dihydrochloride; N-[1-(3,4-Difluorobenzyl)-4-piperidinyl]-6-(trifluoromethyl)-3-pyridazinamine dihydrochloride. Grades: ≥98%. CAS No. 2108806-02-4. Molecular formula: C17H19Cl2F5N4. Mole weight: 445.26. |  |
| JNJ-37822681 dihydrochloride | JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D 2 receptor antagonist with a moderate binding affinity for the dopamine D 2L receptor ( K i =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2108806-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111066A. |  |
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