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| Product | Description | |
|---|---|---|
| JNJ-41443532 | JNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity ( IC 50 =37 nM) and potent functional antagonism ( chemotaxis IC 50 =30 nM). JNJ-41443532 displays a K i of 9.6 μM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR2 antagonist 5. CAS No. 1228650-83-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13499. |  |
| JNJ-41443532 | This active molecular is a CCR2 receptor antagonist which is applicated for the treatment of type-2 diabetes mellitus under the development of Janssen Research & Development. In 2010, Phase-I clinical trials in Type-2 diabetes mellitus was on-going. in Belgium and USA. Uses: Type-2 diabetes mellitus. Synonyms: JNJ-41443532; JNJ 41443532; JNJ41443532; JNJ-41443532 Free Base; N-(2-((1-(trans-4-hydroxy-4-(5-thiazolyl)cyclohexyl)-3-azetidinyl)amino)-2-oxoethyl)-3-(trifluoromethyl)Benzamide. Grades: 98%. CAS No. 1228650-83-6. Molecular formula: C22H25F3N4O3S. Mole weight: 482.52. |  |
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