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| Product | Description | |
|---|---|---|
| JSH-23 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| JSH-23 | JSH-23 is a nuclear factor-kappa B (NF-κB) nuclear translocation inhibitor. JSH-23 inhibits LPS and cytokine-induced nuclear translocation of the p65 subunit of NF-kB as analyzed by EMSA and western blot. JSH-23 treatment significantly reversed the nerve conduction and nerve blood flow deficits seen in diabetic animals. Reduction in mechanical pain threshold was also partially corrected by the treatment. Protein expression studies showed that nuclear translocation of p65/p50 subunit was inhibited by JSH-23 treatment in the sciatic nerve. The treatment also lowered the elevated IL-6, TNF-α, cyclo-oxygenase (COX-2) and inducible nitric oxide synthase (iNOS) levels/expression, indicating reduction in the inflammatory damage of the sciatic nerve. Apart from these effects, JSH-23 also increased Nrf2 and hemeoxygenase-1 (HO-1) levels which could imply its potential in increasing the strength of antioxidant defence. Synonyms: JSH-23; JSH 23; JSH23. Grades: 0.98. CAS No. 749886-87-1. Molecular formula: C16H20N2. Mole weight: 240.35. |  |
| 4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine (JSH-23) | A cell-permeable, selective blocker of nuclear translocation of NF-KB p65. NF-KB activation inhibitor II, JSH-23. Group: Biochemicals. Alternative Names: JSH-23. Grades: Highly Purified. CAS No. 749886-87-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| 4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine | 4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine. Group: Biochemicals. Alternative Names: JSH-23. Grades: Highly Purified. CAS No. 749886-87-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H20N2. US Biological Life Sciences. | Worldwide |
| N- (4-Methyl-2-nitrophenyl) benzenepropanamine | N- (4-Methyl-2-nitrophenyl) benzenepropanamine is an intermediate in the synthesis of a cell-permeable, selective blocker of nuclear translocation of NF-KB p65. NF-KB activation inhibitor II, JSH-23. Group: Biochemicals. Grades: Highly Purified. CAS No. 833454-98-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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