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| Product | Description | |
|---|---|---|
| JX 401 | JX 401, cell-permeable piperidinamide compound, is a reversible and highly potent inhibitor of p38α isoform MAP kinase containing a 4-benzylpiperidine motif. Its IC50 value is 32 nM and displays no activity on the p38γ isoform. It effectively blocks the differentiation of L8 myoblasts to myotubes in a reversible manner and blocks the differentiation of myoblasts and myotubes in mammalian cells in culture. It is not a competitive inhibitor with respect to either ATP or substrate. It is hyperactive in inflammatory diseases and may reverse inflammation. Synonyms: JX-401; JX 401; JX401; 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine; [2-Methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]-methanone; N-(2-Methoxy-4-thiomethyl)benzoyl-4-benzylpiperidine. Grades: ≥98% by HPLC. CAS No. 349087-34-9. Molecular formula: C21H25NO2S. Mole weight: 355.49. |  |
| JX 401 | JX 401. Group: Biochemicals. Grades: Purified. CAS No. 349087-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
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