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Kazusamycin a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Kazusamycin, Kazusamycin A, Antibiotic CL1957B, Antibiotic 81-484, AIDS058215, AIDS-058215, PD 114721, CID6436292, 94664-05-8 (DELETED), LS-185045, 2,10,12,16,18-Nonadecapentaenoic acid, Kazusamycin A, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, 92090-94-3, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,10E,12E,16Z,18E)-, 94664-05-8. Product Category: Heterocyclic Organic Compound. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73. Purity: 0.96. IUPACName: (2E,10E,12E,16Z,18E)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid. Density: 1.109±0.06 g/cm³ (20 °C, 760 mmHg). Product ID: ACM92090943. Alfa Chemistry ISO 9001:2015 Certified.
Kazusamycin A
A minor member of the leptomycin complex isolated from some streptomyces species; an hydroxylated analogue of leptomycin B, a nuclear export inhibitor; exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. Synonyms: 3-HYDROXYLEPTOMYCIN B; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-; CL 1957B, PD 114721. Grades: >95% by HPLC. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73.
Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of Leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines and also shows strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721. Grades: Highly Purified. CAS No. 92090-94-3. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Kazusamycin B
A minor component of the leptomycin complex produced by some streptomyces sp.; an hydroxylated analogue of leptomycin A, a nuclear export inhibitor; displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice; also possesses strong antibacterial and antifungal activity. Synonyms: PD 124895; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-. Grades: >95% by HPLC. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.70.
Kazusamycin B (Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895 )
Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp. It is an hydroxylated analogue of Leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895. Grades: Highly Purified. CAS No. 107140-30-7. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
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