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| Product | Description | |
|---|---|---|
| KB SRC 4 | KB SRC 4. Group: Biochemicals. Grades: Purified. CAS No. 1380088-03-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| KB SRC 4 | KB SRC 4 is a cell-permeable, potent and highly selective c-Src inhibitor with Kd value of 86 nM and Ki value of 44 nM, which is a key signaling kinase in cancer. It displays no inhibition on c-Abl up to 125 μM and is selective between Src family members. It inhibits cell growth in 4T1 mammary carcinoma tumor cells. It has antitumor activity and may be a promising therapeutic potential in the treatment of cancers. Synonyms: 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 1380088-03-8. Molecular formula: C32H23ClN8. Mole weight: 555.03. |  |
| Nitidine chloride | Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis , inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A , ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 13063-04-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0498. |  |
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