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| Product | Description | |
|---|---|---|
| KC01 | KC01 is a covalent inhibitor of ABHD16A. ABHD16A is a phosphatidylserine (PS) lipase that generates lyso-PS in mammalian systems. KC01 can deplete lysoPSs from cells, including lymphoblasts derived from subjects with PHARC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KC01; K C01; K-C01. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.56. Purity: >98%. IUPACName: (Z)-6-(2-oxo-4-tridecyloxetan-3-ylidene)hexanamide. Canonical SMILES: O=C(N)CCCC/C=C1C(OC\1CCCCCCCCCCCCC)=O. Product ID: ACM1646795596. Alfa Chemistry ISO 9001:2015 Certified. Categories: KC-17. |  |
| KC01 | KC01 is an effective inhibitor of ABHD16A , with IC 50 s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646795-59-6. Pack Sizes: 1 mg. Product ID: HY-120299. |  |
| KC01 | KC01 is a selective ABHD16A inhibitor (IC50s values of 90 and 520 nM for human and mouse, respectively). ABHD12 is a major brain Lysophosphatidylserine (lyso-PS) lipase. KC01 was shown to deplete lyso-PSs from cells, including the neurological disease PHARC subject-derived lymphoblasts. Synonyms: (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.6. |  |
| KC02 | KC02 is an inactive control probe for KC01, the inhibitor of ABHD16A. Synonyms: 6-(2-Oxo-4-phenethyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-60-9. Molecular formula: C17H21NO3. Mole weight: 287.4. | |
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