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Product | Description | |
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Kenpaullone Quick inquiry Where to buy Suppliers range | Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively). Uses: Reprogramming. Synonyms: NSC664704; NSC-664704; NSC 664704; 9-Bromopaullone; 1-azakenpaullone; Kenpaullone. Grades: 98%. CAS No. 142273-20-9. Molecular formula: C16H11BrN2O. Mole weight: 327.18. | |
Kenpaullone Quick inquiry Where to buy Suppliers range | Kenpaullone. Group: Biochemicals. Grades: Purified. CAS No. 142273-20-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
KENPAULLONE Quick inquiry Where to buy Suppliers range | kenpaullone, 142273-20-9, 9-Bromopaullone, NSC 664704, NSC-664704, 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one, 9-Bromopaullone;NSC-664704, 9-Bromo-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one, NSC664704, Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-, C16H11BrN2O, NSC-664704(Kenpaullone), MLS002702152, CHEMBL296586, 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one, 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, SR-01000075952, Bromo Paullone, MFCD02683595, Kinome_3565, Tocris-1398, Kenpaullone, >=98%, BiomolKI_000072, Lopac-K-3888, BiomolKI2_000076, D00PWQ, NCIMech_000735, cid_3820, Lopac0_000647, SCHEMBL79889, BDBM7266, GTPL6000, STO175, T72H2BL53P, CHEBI:92658, DTXSID10161994, EX-A702, BCPP000195, HMS3229K10, HMS3262A15, HMS3267F14, HMS3412M10, HMS3650F17, HMS3676M10, BCP02440, Tox21_500647, CCG-35778, CCG-36383, HB1266, HSCI1_000038, s7917, AKOS024456573, BCP9000809, CS-5049, Indolo[3, 9-bromo-7,12-dihydro-,, LP00647, SDCCGSBI-0050627.P004, Kenpaullone - CAS 142273-20-9, SMP2_000306, NCGC00015582-01, NCGC00015582-02, NCGC00015582-03, NCGC00015582-04, NCGC00015582-05, NCGC00015582-06, NCGC00015582-18, NCGC00025143-01, NCGC00025143-02, NCGC00025143-03, NCGC00025143-04, NCGC00261332-01, AC-32896, AS-70762, HY-12302, NCI60_022295, SMR001456311, BB 0301260, EU-0100647, FT-0670607, K0052, F17055, K 3888, K00061, J-007630, J-521618, SR-01000075952-1, SR-01000075952-3, SR-01000075952-6, SR-01000075952-9, BRD-K37312348-001-04-4, BRD-K37312348-001-06-9, SR-01000075952-10, 9-bromo-7,12-dihydroindolo[3,2-d][1]-benzazepin-6(5h)-one, 8-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one, 9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one;NSC 664704, 14-BROMO-8,18-DIAZATETRACYCLO[9.7.0.0(2),?.0(1)(2),(1)?]OCTADECA-1(11),2,4,6,12,14,16-HEPTAEN-9-ONE, 14-bromo-8,18-diazatetracyclo[9.7.0.0;{2,7}.0;{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one, 14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12,14,16-heptaen-9-one, NSC-664704; 9-Bromo-7,12-dihydr9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one. | |
Kenpaullone (8-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one) Quick inquiry Where to buy Suppliers range | The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3ß inhibitor (IC50=23nM). Group: Biochemicals. Alternative Names: 8-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
3-[(4-Ethoxy-1,4-dioxobutyl)amino]-2-pyridinecarboxylic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone. Group: Biochemicals. Alternative Names: 3-[(4-Ethoxy-4-oxobutanoyl)amino]-2-pyridinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 676596-61-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione Quick inquiry Where to buy Suppliers range | A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone derivatives. Group: Biochemicals. Alternative Names: 7,8-Dihydro-5H-pyrido[3,2-b]azepine-6,9-dione. Grades: Highly Purified. CAS No. 676596-63-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Alsterpaullone Quick inquiry Where to buy Suppliers range | Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grades: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3. |