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| Product | Description | |
|---|---|---|
| KH-CB19 | KH-CB19, a CLK1/CLK4 inhibitor, has been found to probably restrain the phosphorylation of serine- and arginine-rich (SR) proteins. IC50: 20 nM for CLK1. Uses: Kh-cb19 is a clk1/clk4 inhibitor that has been found to probably restrain the phosphorylation of serine- and arginine-rich (sr) proteins. Synonyms: KH-CB19; KH CB19; KHCB19. Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate; 2wu7; GTPL8055; 3761AH. Grades: 98%. CAS No. 1354037-26-5. Molecular formula: C15H13Cl2N3O2. Mole weight: 338.19. |  |
| Cdc2-Like Kinase Inhibitor IV, KH-CB19 | The Cdc2-Like Kinase Inhibitor IV, KH-CB19 controls the biological activity of Cdc2-Like KInase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Cdc2-Like Kinase Inhibitor IV, KH-CB19 ((E)-Ethyl-3-(2-amino-1-cyanovinyl)-6,7-dichloro-1-methyl-1H-indole-2-carboxylate) | A cell-permeable N-methylindolyl-enaminonitrile compound that acts as a potent, non-ATP mimetic binding and reversible inhibitor of Clk1 and Dyk1A (IC50=19.7 and 55.2nM, respectively) with moderate to excellent selectivity over Clk3 (IC50=530nM) and against 71-kinases. Shown to suppress phosphorylation of Ser/Arg-rich (SR) proteins, regulate alternative splicing and lower both full-length and alternatively spliced human tissue factor isoforms much more efficiently than Cdc2-Like Kinase Inhibitor, TG003 in HMEC-1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?, Molecular Weight: 338.2. US Biological Life Sciences. |  Worldwide |
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