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| Product | Description | |
|---|---|---|
| KL001 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| KL001 | KL001. Group: Biochemicals. Alternative Names: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide. Grades: Highly Purified. CAS No. 309928-48-1. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C21H22N2O4S, Molecular Weight: 398.48. US Biological Life Sciences. |  Worldwide |
| KL001 | KL001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. In combination with mathematical modeling, our studies using KL001 revealed that CRY1 and CRY2 share a similar functional role in the period regulation. Furthermore, KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KL001; KL-001; KL 001. Product Category: Others. Appearance: Solid powder. CAS No. 309928-48-1. Molecular formula: C21H22N2O4S. Mole weight: 398.48. Purity: >98%. IUPACName: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide. Canonical SMILES: CS(=O)(N(CC(O)CN1C2=C(C3=C1C=CC=C3)C=CC=C2)CC4=CC=CO4)=O. Product ID: ACM309928481. Alfa Chemistry ISO 9001:2015 Certified. Categories: Kl2017. |  |
| KL001 | KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 309928-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108468. |  |
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