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| Product | Description | |
|---|---|---|
| KN-92 | KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell. Synonyms: KN 92; KN92. Grades: >98%. CAS No. 176708-42-2. Molecular formula: C24H25ClN2O3S. Mole weight: 456.98. |  |
| KN-92 - CAS 1135280-28-2 | KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM Kinase II inhibitor. Group: Fluorescence/luminescence spectroscopy. |  |
| KN-92 hydrochloride | KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII). At concentrations up to 25 μM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. Synonyms: KN 92 hydrochloride; KN92 hydrochloride. Grades: >98%. CAS No. 1431698-47-3. Molecular formula: C24H26Cl2N2O3S. Mole weight: 493.45. | |
| KN-92 phosphate | KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93. Synonyms: KN-92 phosphate; KN 92 phosphate; KN92 phosphate. Grades: >98%. CAS No. 1135280-28-2. Molecular formula: C24H28ClN2O7PS. Mole weight: 554.98. | |
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