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| Product | Description | |
|---|---|---|
| KRN7000 | KRN7000 is a synthetic analog of α-galactosylceramide and the marine natural product agelasphin. It is a specific ligand for human and mouse NKT cells and remains the best studied ligand of the lipid-binding MHC class I-like protein CD1d. It protects against LPS-induced shock and displays potent antitumor activity in various in vivo models. Synonyms: a-Gal-Cer N-[(1S,2S,3R)-1-[(a-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide KRN7000. Grades: >99%. CAS No. 158021-47-7. Molecular formula: C50H99NO9. Mole weight: 858.32. |  |
| 1-(2,3,4,6-Tetrakis-O-benzyl)-2,3-bis(tert-butyldimethylsilyloxy) KRN7000 | 1-(2,3,4,6-Tetrakis-O-benzyl)-2,3-bis(tert-butyldimethylsilyloxy) KRN7000 is a strong agonist for Natural Killer T cells. Mostly utilized to facilitate immunotherapy research, it has been associated with autoimmune diseases and certain cancers. Uses: Intermediate for the preparation of krn7000. Synonyms: N- [ (1S, 2S, 3R) -2, 3-Bis [ [ (1, 1-dimethylethyl) dimethylsilyl] oxy] -1- [ [ [2, 3, 4, 6-tetrakis-O- (phenylmethyl) -α -D-galactopyranosyl] oxy] methyl] heptadecyl] hexacosanamide. CAS No. 205371-69-3. Molecular formula: C90H151NO9Si2. Mole weight: 1447.33. | |
| (1S, 2S, 3S, 4S, 5R) -2, 3, 4-Tris (benzyloxy) -5- ( (benzyloxy) methyl) cyclohexyl 2,2,2-Trichloroacetimidate | (1S, 2S, 3S, 4S, 5R) -2, 3, 4-Tris (benzyloxy) -5- ( (benzyloxy) methyl) cyclohexyl 2,2,2-Trichloroacetimidate is an intermediate in the synthesis of KRN7000 (K660000), an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| α-Galactosylceramide | α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-GalCer; KRN7000. CAS No. 158021-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-102022. |  |
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