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| Product | Description | |
|---|---|---|
| KX2-391 | KX2-391 is an orally bioavailable small molecule Src kinase inhibitor with potential antineoplastic activity. Unlike other Src kinase inhibitors which bind to the ATP-binding site, Src kinase inhibitor KX2-391 specifically binds to the peptide substrate binding site of Src kinase; inhibition of kinase activity may result in the inhibition of primary tumor growth and the suppression of metastasis. Src tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. Uses: Enzyme inhibitors. Synonyms: KX01, KX-01, KX 01, KX2-391; KX-2-391; KX 2-391; KX2391; KX-2391; KX 2391; Tirbanibulin. CAS No. 897016-82-9. Molecular formula: C26H29N3O3. Mole weight: 431.53. |  |
| KX2-391 dihydrochloride | KX2-391 2Hcl is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Synonyms: KX2-391 dihydrochloride; 1038395-65-1; KX2-391 (dihydrochloride); Tirbanibulin (dihydrochloride); N-benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]acetamide;dihydrochloride. Grades: >98%. CAS No. 1038395-65-1. Molecular formula: C26H31Cl2N3O3. Mole weight: 504.45. | |
| Tirbanibulin | Tirbanibulin (KX2-391) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391; KX-01. CAS No. 897016-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340. |  |
| Tirbanibulin dihydrochloride | Tirbanibulin (dihydrochloride) (KX2-391 (dihydrochloride)) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391 dihydrochloride; KX-01 dihydrochloride. CAS No. 1038395-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340A. | |
| Tirbanibulin Mesylate | Tirbanibulin Mesylate (KX2-391 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391 Mesylate; KX01 Mesylate. CAS No. 1080645-95-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340B. | |
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