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| Product | Description | |
|---|---|---|
| L-168,049 | L-168,049. Group: Biochemicals. Grades: Purified. CAS No. 191034-25-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| L-168,049 | L-168,049 is a non-peptidyl, very selective and potent human glucagon receptor (hGR) antagonist. It displays high affinity to human GR with IC50 value of 3.7 nM, but shows moderate affinity for murine and canine GRs. It inhibits glucagon-stimulated cAMP synthesis in murine liver membranes and in CHO cells expressing hGR. It is orally active in vivo. Synonyms: L-168,049; L 168,049; L168,049; 2-(4-Pyridyl)-5-(4-chlorophenyl)-3-(5-bromo-2-propyloxyphenyl)pyrrole; 4-[3-(5-Bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine. Grades: ≥99% by HPLC. CAS No. 191034-25-0. Molecular formula: C24H20BrClN2O. Mole weight: 467.79. |  |
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