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L-748,337 L-748,337. Group: Biochemicals. Grades: Purified. CAS No. 244192-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
L-748,337 L-748,337 is a selective and competitive β3-adrenoceptor antagonist with Ki value of 4.0 nM. It can inhibit agonist-induced relaxation of smooth muscle and lipolysis in rhesus monkey adipocytes. It also inhibits cAMP accumulation in response to isoproterenol. It reduces apoptosis, iNOS expression and attenuates nitric oxide-induced cell proliferation in a melanoma cell line. Synonyms: L-748337; L 748337; L748337. N- [ [3- [ (2S) -2-Hydroxy-3- [ [2- [4- [ (phenylsulfonyl) amino] phenyl] ethyl] amino] propoxy] phenyl] methyl] -acetamide. Grades: ≥98% by HPLC. CAS No. 244192-94-7. Molecular formula: C26H31N3O5S. Mole weight: 497.61. BOC Sciences 10

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