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| Product | Description | |
|---|---|---|
| L-798,106 | L-798,106. Group: Biochemicals. Grades: Purified. CAS No. 244101-02-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| L-798,106 | L-798,106 is a potent and highly selective prostanoid receptor EP3 antagonist wth Ki value of 0.3 nM. It is used in prostanoid receptor signaling studies that regulates the central excitatory effects of PGE(2) and COX-2 levels on PVN neurons. It has been used to tease out EP3 agonist activity both in vitro and in vivo. It successfully blocks the EP3 agonist activity of sulprostone on guinea pig vas deferens and trachea at 0.2 μM. It attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo. Synonyms: L-798,106; L 798,106; L798,106. N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; L-798106; (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; CM 9; GW 671021; (E)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide. Grades: ≥99% by HPLC. CAS No. 244101-02-8. Molecular formula: C27H22BrNO4S. Mole weight: 536.44. |  |
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