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| Product | Description | |
|---|---|---|
| L-838417 | L-838417. Group: Biochemicals. Alternative Names: 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine. Grades: Highly Purified. CAS No. 286456-42-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H19F2N7O. US Biological Life Sciences. |  Worldwide |
| L-838417. (3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine) | A ligand of GABAA receptors. Group: Biochemicals. Alternative Names: 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7-tert-Butyl-6-chloro-3-(2,5-difluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine | Intermediate for the preparation of L-838417. Group: Biochemicals. Alternative Names: 6-Chloro-3-(2,5-difluorophenyl)-7-(1,1-dimethylethyl)-1,2,4-triazolo[4,3-b]pyridazine. Grades: Highly Purified. CAS No. 286456-54-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| L-838,417 | L-838,417 is a subtype-selective GABAA receptor partial agonist. It selectively binds to α2, α3 and α5 subunits with Ki values of 0.67, 0.67 and 2.25 nM respectively, but it shows no efficacy at α1 (α1-sparing). It shows non-sedative antinociceptive, anxiolytic and anti-inflammatory activity in vivo. It was developed by Merck. Uses: Gaba-a receptor agonists. Synonyms: L838417; L 838417; L-838417; 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine; 5-({[7-tert-butyl-3-(2,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1H-1,2,4-triazole; L-838417. Grades: ≥98% by HPLC. CAS No. 286456-42-6. Molecular formula: C19H19F2N7O. Mole weight: 399.40. |  |
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