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L-AP4 L-AP4. Group: Biochemicals. Grades: Purified. CAS No. 23052-81-5. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
L-AP4 L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus. L-AP4 is a synaptic depressant. Synonyms: L-(+)-2-Amino-4-phosphonobutyric acid; (2S)-2-amino-4-phosphonobutanoic acid; L-AP4; L AP4; LAP4. Grades: ≥99% by HPLC. CAS No. 23052-81-5. Molecular formula: C4H10NO5P. Mole weight: 183.1. BOC Sciences 10
L-AP4 L-AP4 (L-APB) is a potent and specific agonist for the group III mGluRs , with EC 50 s of 0.13, 0.29, 1.0, 249 μM for mGlu 4 , mGlu 8 , mGlu 6 and mGlu 7 receptors, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-APB. CAS No. 23052-81-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100781A. MedChemExpress MCE
L-(+)-2-Amino-4-phosphonobutyric Acid (L-AP4) Phosphonic acid analog of L-glutamic acid. A selective group III metabotropic glutamate receptor agonist. Also a potent, pathway-specific synaptic depressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 23052-81-5. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 4
Worldwide
MPPG MPPG is a potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons, showing selectivity over (1S,3S)-ACPD-induced effects. MPPG should be useful in determining the roles of group II and III mGluRs in the central nervous system. Synonyms: (RS)-α-Methyl-4-phosphonophenylglycine. CAS No. 169209-65-8. Molecular formula: C9H12NO5P. Mole weight: 245.17. BOC Sciences 11
MSOP MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent K D of 51 μM for the L-AP4-sensitive presynaptic mGluR. Uses: Scientific research. Group: Signaling pathways. CAS No. 66515-29-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101226. MedChemExpress MCE
MSOP MSOP is a selective group III metabotropic glutamate receptor (mGluR) antagonist. MSOP exhibits an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. MSOP has no effect on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons. Synonyms: (RS)-α-Methylserine-O-phosphate; Alpha-MSOP; Alpha-methylserine-O-phosphate; 2-amino-2-methyl-3-phosphonooxypropanoic acid. CAS No. 66515-29-5. Molecular formula: C4H10NO6P. Mole weight: 199.1. BOC Sciences 10

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