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| Product | Description | |
|---|---|---|
| L002 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| L002 | L002. Group: Biochemicals. Grades: Purified. CAS No. 321695-57-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| OG-L002 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| p300/CBP Inhibitor VI, L002 (4- (4-Methoxyphenyl sulfonyl oxyimino) -2, 6-di methyl -2, 5-cyclohexadien-1-one, GCN5 Inhibitor III, Histone Acetyltransferase Inhibitor IX, PCAF Inhibitor IV) | A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. | Worldwide |
| DiagPoly Carboxyl Fluorescent Polystyrene Particles, Green, 0.05 μm | DiagPoly Carboxyl Fluorescent Polystyrene Particles, Green, 0.05 μm (# DCFG-L002) are encapsulated with green fluorophores (excitation: 460 nm, emission: 500 nm) and functionalized with carboxyl groups (COOH) on the surface for the covalent attachment of proteins, peptides and nucleic acids. The density of liquid suspension is 1.05-1.06 g/mL. Sonicate/Vortex the microspheres before each use. Uses: Imaging and diagnostic purposes for signal enhancement and binding detection, fluid tracing, fluid mechanics studies, cell tracking, phagocytosis studies, latex agglutination tests, fluorescence microscopy, instrument calibration and biomedical technology research. Pack Sizes: 1 mL, 2 mL, 3 mL, 10 mL. Product ID: DCFG-L002. |  |
| DiagPoly Carboxyl Fluorescent Polystyrene Particles, Orange, 0.2 μm | DiagPoly Carboxyl Fluorescent Polystyrene Particles, Orange, 0.2 μm (# DCFO-L002) are encapsulated with orange fluorophores (excitation: 530 nm, emission: 582 nm) and functionalized with carboxyl groups (COOH) on the surface for the covalent attachment of proteins, peptides and nucleic acids. The density of liquid suspension is 1.05-1.06 g/mL. Sonicate/Vortex the microspheres before each use. Uses: Imaging and diagnostic purposes for signal enhancement and binding detection, fluid tracing, fluid mechanics studies, cell tracking, phagocytosis studies, latex agglutination tests, fluorescence microscopy, instrument calibration and biomedical technology research. Pack Sizes: 1 mL, 2 mL, 3 mL, 10 mL. Product ID: DCFO-L002. | |
| DiagPoly Plain Polystyrene Particles, 0.05 μm | Plain PS Particles, 0.05 μm, 10 mg/mL, dispersed in DI water. Uses: Cell sorting, immunoprecipitation, biosensing, in vivo and in vitro sensor, coating materials for contrast agents and anti-cancer drugs. Pack Sizes: 5 mL. Product ID: DMP-L002. | |
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