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| Product | Description | |
|---|---|---|
| l189 | L189 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 64232-83-3. Molecular formula: C11H10N4OS?xH2O. Mole weight: C11H10N4OS. Purity: ≥98.0%. Canonical SMILES: OC1=NC(S)=NC(N)=C1/N=C/C2=CC=CC=C2. Product ID: ACM64232833. Alfa Chemistry ISO 9001:2015 Certified. Categories: L129A1. |  |
| L189 | L189. Group: Biochemicals. Grades: Purified. CAS No. 64232-83-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| L189 | L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding. L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. Synonyms: L189; L 189; L-189. Grades: 98%. CAS No. 64232-83-3. Molecular formula: C11H10N4OS. Mole weight: 246.29. |  |
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