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Lacto-N-neotetraose is a valuable biomolecule predominantly utilized as a prebiotic supplement. Additionally, Lacto-N-neotetraose has shown potential in modulating the immune system, making it a promising candidate for the research of various autoimmune disorders. Synonyms: Gal-b-1,4-GlcNAc-b-1,3-Gal-b-1,4-Glc; LNnT; O-β-D-galactopyranosyl-(1?4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1?3)-O-β-D-galactopyranosyl-(1?4)-D-Glucose; N-Neotetraose; beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc; beta-D-galactosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucose. Grades: ≥95%. CAS No. 13007-32-4. Molecular formula: C26H45NO21. Mole weight: 707.63.
Lacto-N-neotetraose
Lacto-N-neotetraose (LNnT) is an endogenous metabolite. Lacto-N-neotetraose can inhibit TNF-α induced IL-8 secretion in immature epithelial cells. Lacto-N-neotetraose has anti-inflammatory avtivity, and can improve the wound closure [1] [2] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: LNnT. CAS No. 13007-32-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9445.
Lacto-N-neotetraose-GEL
3-Sialyllacto-N-neotetraose
3-Sialyllacto-N-neotetraose is an acclaimed compound, is specifically formulated to address gastrointestinal disorders in a scientifically advanced manner. Its groundbreaking composition acts as a potent prebiotic catalyst, efficaciously nurturing the flourishing of advantageous gut microflora. Synonyms: 3-SLNnT LS tetrasaccharide d Sialylated lacto-N-neotetraose. CAS No. 100789-83-1. Molecular formula: C37H62N2O29. Mole weight: 998.88.
lacto-N-biosidase
The enzyme from Streptomyces specifically hydrolyses the terminal lacto-N-biosyl residue (β-D-Gal-(1?3)-D-GlcNAc) from the non-reducing end of oligosaccharides with the structure β-D-Gal-(1?3)-β-D-GlcNAc-(1?3)-β-D-Gal-(1?R). Lacto-N-hexaose (β-D-Gal-(1?3)-β-D-GlcNAc-(1?3)-β-D-Gal-(1?3)-β-D-GlcNAc-(1?3)-β-D-Gal-(1?4)-D-Glc) is hydrolysed to form first lacto-N-tetraose plus lacto-N-biose, with the subsequent formation of lactose. Oligosaccharides in which the non-reducing terminal Gal or the penultimate GlcNAc are replaced by fucose or sialic acid are not substrates. Asialo GM1 tetraose (β-D-Gal-(1?3)-β-D-GalNAc-(1?3)-β-D-Gal-(1?4)-D-Glc) is hydrolysed very slowly, but lacto-N-neotetraose (β-D-Gal-(1?4)-β-D-GalNAc-(1?3)-β-D-Gal-(1?4)-D-Glc) is not a substrate. Group: Enzymes. Enzyme Commission Number: EC 3.2.1.140. CAS No. 146359-52-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3823; lacto-N-biosidase; EC 3.2.1.140; 146359-52-6. Cat No: EXWM-3823.
4-Nitrophenyl b-lacto-N-neotetraoside
4-Nitrophenyl β-lacto-N-neotetraoside is extensively employed in the field of biomedicine for the purpose of probing and exploring the activity of the esteemed β-galactosidase enzyme. Functioning as a paramount substrate, it effectively facilitates the identification and precise quantification of β-galactosidase levels within intricate biological samples. This remarkable product assumes a pivotal role in the progressive investigation of lysosomal storage disorders, lactose intolerance issues, as well as other maladies intricately associated with the deficiency of β-galactosidase. Synonyms: Gal-b-1,4-GlcNAc-b-1,3-Gal-b-1,4-Glc-b-pNP. CAS No. 197526-33-3. Molecular formula: C32H48N2O23. Mole weight: 828.72.
Endo-β-galactosidase from Bacteroides fragilis, Recombinant
Endo-β-Galactosidase is an enzyme that hydrolyzes internal β-galactosidic linkages of oligosaccharides in poly-N-acetyl-lactosamine structures. This enzyme resembles the Escherichia freundii enzyme due to its specificity towards bovine corneal keratan sulphate, milk oligosaccharides and the glycolipids lacto-N-neotetraosylceramide and lacto-N-tetraosylceramide. Group: Enzymes. Synonyms: β-Galactosidase bacterial; Keratanase; Endo-β-galactosidase; keratan sulfate endogalactosidase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.103. Enzyme Commission Number: EC 3.2.1.103. CAS No. 55072-01-0. Endo-β-galactosidase. Mole weight: ~32 kDa. Activity: >14 U/ml; Specific Activity: >140 U/mg protein. Storage: 2-8°C. Form: Sterile-filtered in 20 mM Tris-HCl, pH 7.5. Source: E. coli. Species: Bacteroides fragilis. β-Galactosidase bacterial; Keratanase; Endo-β-galactosidase; keratan sulfate endogalactosidase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.103. Cat No: NATE-1413.
Lacto-N-neotetraosa-APD-HSA
N-Acetylglucosamine endo-β-galactosidase 16C from Clostridium perfringens, Recombinant
Endo-β-Galactosidase is an enzyme that hydrolyzes internal β-galactosidic linkages of oligosaccharides in poly-N-acetyl-lactosamine structures. This enzyme resembles the Escherichia freundii enzyme due to its specificity towards bovine corneal keratan sulphate, milk oligosaccharides and the glycolipids lacto-N-neotetraosylceramide and lacto-N-tetraosylceramide. Group: Enzymes. Synonyms: β-Galactosidase bacterial; Keratanase; Endo-β-galactosidase; keratan sulfate endogalactosidase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.103. Enzyme Commission Number: EC 3.2.1.-. Purity: >90% by SDS-PAGE. Endo-β-galactosidase. Mole weight: 33.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Clostridium perfringens. β-Galactosidase bacterial; Keratanase; Endo-β-galactosidase; keratan sulfate endogalactosidase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.-; N-Acetylglucosamine endo-β-galactosidase 16C. Cat No: NATE-1412.
Neolactotetraosylceramide
Neolactotetraosylceramide is a highly valuable compound with immunostimulatory and immune-regulatory activities, extending to the research of autoimmune diseases, cancer immunotherapy and the modulation of immune responses. Synonyms: Globosides; Gal (b1-4) GlcNAc (b1-3) Gal (b1-4) Glc b1-1 Ceramide; Lacto-N-neotetraosyl ceramide. CAS No. 153565-90-3. Molecular formula: C62H114N2O23. Mole weight: 1255.57.
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