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| Product | Description | |
|---|---|---|
| Lalistat 2 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Lalistat 2 | Lalistat 2 is a lysosomal acid lipase inhibitor with IC50 value of 152 nM. Lalistat-2 can affect lipid droplets morphology and localization. Synonyms: 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate. Grades: ≥98% by HPLC. CAS No. 1234569-09-5. Molecular formula: C13H20N4O2S. Mole weight: 296.39. |  |
| Lalistat 2 | Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells [1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1234569-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128144. |  |
| Lalistat 1 | Lalistat 1 is a lysosomal acid lipase inhibitor with IC50 value of 68 nM. It can block LAL-mediated lipid hydrolysis of acetylated LDL and reduce efflux of cholesterol from lipid-loaded cells. Synonyms: 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate. Grades: ≥98% by HPLC. CAS No. 501104-16-1. Molecular formula: C12H18N4O3S. Mole weight: 298.36. | |
| Lalistat 1 | Lalistat 1 is a potent, selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM. Lalistat 1 is a inhibitor of immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or ?-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 501104-16-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116815. | |
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