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| Product | Description | |
|---|---|---|
| Larotaxel | Larotaxel is a semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. Larotaxel penetrates the blood brain barrier. Synonyms: XRP9881; PNU 100940. CAS No. 156294-36-9. Molecular formula: C45H53NO14. Mole weight: 831.912. |  |
| Larotaxel | Larotaxel (RPR 109881A) is a taxane analog with a broad spectrum of activity and different toxicity profile and with the possible advantages of surpassing some mechanisms of resistance and penetrating into the CNS. Group: Biochemicals. Alternative Names: (αR. Grades: Highly Purified. CAS No. 156294-36-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Larotaxel | Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XRP9881. CAS No. 156294-36-9. Pack Sizes: 1 mg. Product ID: HY-125374. |  |
| N,O-Isopropylidene Larotaxel | Intermediate in the synthesis of taxol analogs. Group: Biochemicals. Alternative Names: [1S-[1α, 2α, 4α(4R*, 5S*), 7 β , 8aS * , 9a α , 10a α , 12a α , 12b α ] ] -2, 2-Di methyl -4-phenyl -3, 5-oxazolidinedicarboxyl ic Acid 5-[7, 12a-Bis(acetyloxy)-1-(benzoyloxy)-1, 3, 4, 7, 8, 9, 9a, 10, 10a, 12, 12a, 12b-dodecahydro-2-hydroxy-5, 13, 13-trimethyl-8-oxo-2, 6-methano-2H-cyclodeca[3, 4]cyclopropa[4, 5]benz[1, 2-b]oxet-4-yl] 3-(1,1-dimethylethyl) Ester. Grades: Highly Purified. CAS No. 168120-68-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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