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Lerisetron Lerisetron is a potent 5-HT 3 antagonists and possess high-affinity binding for the 5-HT 3 receptors with pK i value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143257-98-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105090. MedChemExpress MCE
Lerisetron Lerisetron is a serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located peripherally on vagus nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, which may result in suppression of chemotherapy-induced nausea and vomiting. Synonyms: 1-Benzyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole; 1-benzyl-2-(piperazin-1-yl)-1H-benzimidazole. CAS No. 143257-98-1. Molecular formula: C18H20N4. Mole weight: 292.39. BOC Sciences 11

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