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Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA594. CAS No. 878672-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15258.
Lesinurad
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body. Synonyms: 2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid; RDEA 594; Zurampic; [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid; Lesinida. Grades: >98%. CAS No. 878672-00-5. Molecular formula: C17H14BrN3O2S. Mole weight: 404.28.
Lesinurad Impurity 11 is an intermediate of Lesinurad, a HEK293 cell-based inhibitor. Synonyms: Methyl 2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetate; [[4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid methyl ester; Acetic acid, 2-[[4-(4-cyclopropyl-1-naphthalenyl)-4h-1,2,4-triazol-3-yl]thio]-, methyl ester. Grades: >95%. CAS No. 1533519-85-5. Molecular formula: C18H17N3O2S. Mole weight: 339.42.
Lesinurad Impurity 15
an intermediate of Lesinurad. Synonyms: 1-cyclopropylnaphthalen. Grades: > 95%. CAS No. 25033-19-6. Molecular formula: C13H12. Mole weight: 168.24.
Lesinurad Impurity 16
An intermediate of Lesinurad, a urate transporter inhibitor used for the treatment of high blood uric acid levels associated with gout. Synonyms: Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate. Grades: > 95%. CAS No. 878671-99-9. Molecular formula: C18H16BrN3O2S. Mole weight: 418.32.
Lesinurad Impurity 18
an intermediate of Lesinurad. Synonyms: [[5-chlorine-4-(4-bromo-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid. Grades: > 95%. Molecular formula: C14H9BrClN3O2S. Mole weight: 398.67.
Lesinurad Impurity 19
an intermediate of Lesinurad. Synonyms: 5-Amino-1-(2-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol. Grades: > 95%. Molecular formula: C15H14N4S. Mole weight: 282.37.
an intermediate of Lesinurad. Synonyms: [[4-(4-bromo-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid. Grades: > 95%. Molecular formula: C14H10BrN3O2S. Mole weight: 364.22.
Lesinurad Impurity C
an intermediate of Lesinurad. Synonyms: [[4-(1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid. Grades: > 95%. CAS No. 1038366-57-2. Molecular formula: C14H11N3O2S. Mole weight: 285.33.
Lesinurad Impurity D
an intermediate of Lesinurad. Synonyms: [[5-bromo-4-(4-bromo-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid. Grades: > 95%. Molecular formula: C14H9Br2N3O2S. Mole weight: 443.12.
Lesinurad Impurity G
an intermediate of Lesinurad. Synonyms: 5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-hydroxy. Grades: > 95%. Molecular formula: C15H12BrN3O. Mole weight: 330.19.
Lesinurad Impurity H
an intermediate of Lesinurad. Synonyms: 5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole. Grades: > 95%. Molecular formula: C15H12BrN3. Mole weight: 314.19.
Lesinurad Impurity I
an intermediate of Lesinurad. Synonyms: [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]oxo]-acetic Acid. Grades: > 95%. Molecular formula: C17H14BrN3O3. Mole weight: 388.22.
Lesinurad sodium
Lesinurad sodium is an once-daily inhibitor of URAT1, which is a transporter in the kidney that regulates uric acid excretion from the body. Synonyms: sodium 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate; sodium Lesinurad; RDEA594 sodium; RDEA 594 sodium; RDEA-594 sodium; Zurampic sodium; Acetic acid, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, sodium salt (1:1). Grades: >98%. CAS No. 1151516-14-1. Molecular formula: C17H13BrN3NaO2S. Mole weight: 426.26.
Lesinurad sodium
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA-594 sodium. CAS No. 1151516-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15258A.
1-Cyclopropyl-2-nitro-naphthalene
1-Cyclopropyl-2-nitro-naphthalene is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1802080-61-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H11NO2, Molecular Weight: 213.23. US Biological Life Sciences.
2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038366-57-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H11N3O2S, Molecular Weight: 285.32. US Biological Life Sciences.
2-[[5-Bromo-4-(1-cyclopropyl-2-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-94-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences.
2-[[5-Bromo-4-(4-propyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-96-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H16BrN3O2S, Molecular Weight: 406.3. US Biological Life Sciences.
2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences.
2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1210330-64-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H10BrN3O2S, Molecular Weight: 364.22. US Biological Life Sciences.
Worldwide
2-Cyclopropyl-1-nitro-naphthalene
2-Cyclopropyl-1-nitro-naphthalene is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 52331-35-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H11NO2, Molecular Weight: 213.23. US Biological Life Sciences.