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| Product | Description | |
|---|---|---|
| Lesogaberan | Lesogaberan is a potent and selective GABAB receptor agonist that limit the clinical use of baclofen for the treatment of GERD. Uses: Gaba b receptor agonists. Synonyms: AZD-3355; AZD 3355; AZD3355; Lesogaberan.[(2R)-3-amino-2-fluoropropyl]-hydroxy-oxophosphanium. Grades: ≥98%. CAS No. 344413-67-8. Molecular formula: C3H9FNO2P. Mole weight: 141.03. |  |
| Lesogaberan hydrochloride | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-3355 hydrochloride. CAS No. 2925644-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10061B. |  |
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