Leukotriene C4 Suppliers USA
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Product | Description | |
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Leukotriene c4 Quick inquiry Where to buy Suppliers range | Colorless liquid. Group: Main Products. Alternative Names: Leukotriene C4 Lipid. Grades: 97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.77. | |
Leukotriene C4 Quick inquiry Where to buy Suppliers range | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4; 5S,6R-Ltc(sub 4); 6R-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5S-hydroxyicosa-7E,9E,11Z,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.78. | |
Leukotriene C4 methyl ester Quick inquiry Where to buy Suppliers range | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4 methyl ester; Leukotriene C4 monomethyl ester. Grades: ≥97%. CAS No. 73958-10-8. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
11-trans Leukotriene C4 Quick inquiry Where to buy Suppliers range | 11-trans Leukotriene C4 is a C-11 double bond isomer of LTC4. Group: Biochemicals. Grades: Highly Purified. CAS No. 74841-69-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences. | Worldwide |
11-Trans leukotriene C4 Quick inquiry Where to buy Suppliers range | 11-Trans leukotriene C4 is a C-11 double bond isomer of LTC4. Synonyms: 11-trans LTC4; Leucotriene C4. Grades: ≥97%. CAS No. 74841-69-3. Molecular formula: C30H47N3O9S. Mole weight: 625.8. | |
14,15-Leukotriene C4 Quick inquiry Where to buy Suppliers range | 14,15-Leukotriene C4 is an acute inflammatory mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 75290-60-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences. | Worldwide |
N-methyl Leukotriene C4 Quick inquiry Where to buy Suppliers range | N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of Leukotriene C4 (LTC4) that is not readily metabolized to LTD4 and LTE4. It acts as a potent and selective CysLT2 receptor agonist. Synonyms: N-methyl LTC4. Grades: ≥97%. CAS No. 131391-65-6. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid Quick inquiry Where to buy Suppliers range | 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. | |
1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl ) methyl ] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1- methyl ethyl) phenyl] propyl ] thio] methyl cyclopropaneacetic Acid Quick inquiry Where to buy Suppliers range | 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl ) methyl ] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1- methyl ethyl) phenyl] propyl ] thio] methyl cyclopropaneacetic Acid is derived from Montelukast Methyl Ester (M568080), which is an impurity of the antiasthmatic drug Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an anti-asthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C41H46ClNO5S2, Molecular Weight: 732.39. US Biological Life Sciences. | Worldwide |
2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast Quick inquiry Where to buy Suppliers range | 2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast is an impurity of Zafirlukast (Z125000); a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1160235-26-6. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C47H48N4O10S2, Molecular Weight: 893.03. US Biological Life Sciences. | Worldwide |
2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast-d3 Quick inquiry Where to buy Suppliers range | 2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast-d3 is the isotope labelled analog of 2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast (M265710); an impurity of Zafirlukast (Z125000) which is a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C47H45D3N4O10S2, Molecular Weight: 896.05. US Biological Life Sciences. | Worldwide |
2-Chloro Zafirlukast-d7 Quick inquiry Where to buy Suppliers range | 2-Chloro Zafirlukast-d7 is the isotope labelled analog of 2-Chloro Zafirlukast (C424225); an impurity of Zafirlukast (Z125000) which is a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C31H25D7ClN3O6S, Molecular Weight: 617.16. US Biological Life Sciences. | Worldwide |
2-((E)-3-((1S)-1-((tert-Butyldimethylsilyl)oxy)-3-(2-(2-((tert-butyldimethylsilyl)oxy)oxiran-2-yl)phenyl)propyl)styryl)-7-chloroquinoline 1-Oxide Quick inquiry Where to buy Suppliers range | 2-((E)-3-((1S)-1-((tert-Butyldimethylsilyl)oxy)-3-(2-(2-((tert-butyldimethylsilyl)oxy)oxiran-2-yl)phenyl)propyl)styryl)-7-chloroquinoline 1-Oxide is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Grades: 98%. Molecular formula: C40H52ClNO4Si2. Mole weight: 702.47. | |
AM679 Quick inquiry Where to buy Suppliers range | AM679 is a drug which acts as a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP). This protein is involved in the production of cysteinyl leukotrienes which are involved in inflammation, and AM679 has anti-inflammatory effects in animal studies. AM679 also showed potent inhibition of leukotrienes in human blood and in a rodent bronchoalvelolar lavage (BAL) challenge model. Research showed AM679 reduces inflammation in the respiratory syncytial virus-infected mouse eye. Synonyms: AM-679; AM 679; AM679; UNII-65KJ8P7M9D; CHEMBL595092; SCHEMBL503239; 65KJ8P7M9D. Grades: >98%. CAS No. 1206880-66-1. Molecular formula: C40H44N4O5S. Mole weight: 692.87. | |
BW-B 70C Quick inquiry Where to buy Suppliers range | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
FPL 55712 Quick inquiry Where to buy Suppliers range | FPL 55712 is a leukotriene receptor antagonist that inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Synonyms: FPL 55712; FPL55712; FPL-55712; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 40785-97-5. Molecular formula: C27H30O9. Mole weight: 498.52. | |
FTY720 Hydrochloride (Gilenya, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol. HCl, Fingolimod) Quick inquiry Where to buy Suppliers range | Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when phosphorylated by sphingosine kinase. Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 activity enhancer. Cytosolic phospholipase A2 inhibitor, independent of sphingosine 1-phosphate receptors. Autophagy inducer. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
Montelukast Acyl-β-D-glucuronide Acetic Acid Salt Quick inquiry Where to buy Suppliers range | Montelukast Acyl-β-D-glucuronide Acetic Acid Salt is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-O- ({1-[ ({ (1R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetyl) -α -D-erythro-hexopyranuronic acid acetate (1:1); α-D-erythro-Hexopyranuronic acid, 1- [2- [1- [ [ [ (1R) -1- [3- [ (E) -2- (7-chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropyl] acetate] , acetate (1:1) (salt); 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetate] β-D-Glucopyranuronic Acid Acetic Acid Salt; Montelukast M1 Acetic acid Salt. Grades: ≥95%. Molecular formula: C43H48ClNO11S. Mole weight: 822.36. | |
Montelukast-Acyl-Glucuronide Quick inquiry Where to buy Suppliers range | An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1-O-[2-[1-[[ (R) -1-[3-[ (E) -2- (7-Chloroquinolin-2-yl) ethenyl]phenyl]-3-[2- (1-methyl-1-hydroxyethyl) phenyl]propylthio]methyl]cyclopropan-1-yl]acetyl]-beta-D-glucopyranuronic acid. Grades: >95%. CAS No. 188717-17-1. Molecular formula: C41H44ClNO9S. Mole weight: 762.31. | |
Montelukast Bis-sulfide (mixture of diastereomers) Quick inquiry Where to buy Suppliers range | Montelukast Bis-sulfide (mixture of diastereomers) is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1- [ [ [ (1R) -1- [3- [ (1R, S) -1- [ [ [1- (Carboxymethyl) cyclopropyl] methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid; Montelukast Michael Aduct. CAS No. 1242260-05-4. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. | |
Montelukast Dicyclohexylamine Salt Quick inquiry Where to buy Suppliers range | Montelukast is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A selective leukotriene d4-receptor antagonist. used as an antiasthmatic. Synonyms: 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic N-Cyclohexylcyclohexanamine; Montelukast DCHA. Grades: 95%. CAS No. 577953-88-9. Molecular formula: C47H59ClN2O3S. Mole weight: 767.50. | |
Montelukast R, R-Isomer Quick inquiry Where to buy Suppliers range | An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 2- (1- ( ( ( (R) -1- (3- ( (R) -1- ( ( (1- (carboxymethyl) cyclopropyl) methyl) thio) -2- (7-chloroquinolin-2-yl) ethyl) phenyl) -3- (2- (2-hydroxypropan-2-yl) phenyl) propyl) thio) methyl) cyclopropyl) acetic acid. Grades: > 95%. Molecular formula: C41H46ClNO5S2. Mole weight: 732.41. | |
R112 Quick inquiry Where to buy Suppliers range | R112 is a Syk inhibitor. R112 inhibited degranulation induced by anti-IgE cross-linking in mast cells (tryptase release, effective concentration for 50% inhibition [EC(50)] = 353 nmol/L) or basophils (histamine release, EC(50) = 280 nmol/L), and by allergen (dust mite) in basophils (histamine release, EC(50) = 490 nmol/L). R112 also blocked leukotriene C4 production and all proinflammatory cytokines tested. Subsequent molecular characterization indicated that R112 is an ATP-competitive spleen tyrosine kinase (Syk) inhibitor (inhibitory constant [K(I)] = 96 nmol/L). R112 was able to completely inhibit all three IgE-induced mast cell functions: degranulation, lipid mediator production, and cytokine production. R112 and its analogues offer a new modality in the treatment of allergic rhinitis. Synonyms: R112; R 112; R-112. CAS No. 575474-82-7. Molecular formula: C16H13FN4O2. Mole weight: 312.3. | |
(S, E) -2- (3- (1- ( (tert-Butyldimethylsilyl) oxy) -3- (2- (1- ( (tert-butyldimethylsilyl) oxy) vinyl) phenyl) propyl) styryl) -7-chloroquinoline Quick inquiry Where to buy Suppliers range | (S, E) -2- (3- (1- ( (tert-Butyldimethylsilyl) oxy) -3- (2- (1- ( (tert-butyldimethylsilyl) oxy) vinyl) phenyl) propyl) styryl) -7-chloroquinoline is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C40H52ClN2Si2. Mole weight: 652.48. |