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Leukotriene E4 is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid; LTE4. Grades: ≥97%. CAS No. 75715-89-8. Molecular formula: C23H37NO5S. Mole weight: 439.61.
Leukotriene E4
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma. Uses: Scientific research. Group: Natural products. Alternative Names: LTE4. CAS No. 75715-89-8. Pack Sizes: 25 μg (227.47 μM * 250 μL in Ethanol); 50 μg (227.47 μM * 500 μL in Ethanol); 100 μg (227.47 μM * 1 mL in Ethanol). Product ID: HY-113465.
Leukotriene E4 methyl ester
Leukotriene E4 methyl ester is a derivate of Leukotriene E4, which is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, 1-methyl ester, (5S,6R,7E,9E,11Z,14Z)-; 1-Methyl (5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoate; 7,9,11,14-Eicosatetraenoic acid, 6-[(2-amino-2-carboxyethyl)thio]-5-hydroxy-, 1-methyl ester, [5S-[5R*,6S*(S*),7E,9E,11Z,14Z]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteine; LTE4, methyl ester; leukotriene E4 monomethyl ester. Grades: ≥95%. CAS No. 89461-65-4. Molecular formula: C24H39NO5S. Mole weight: 453.64.
11-trans Leukotriene E4
11-trans Leukotriene E4 is an equipotent C-11 double bond isomer of LTE4. Group: Biochemicals. Grades: Highly Purified. CAS No. 75715-88-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences.
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14,15-Leukotriene E4
14,15-Leukotriene E4 is a Leukotriene that increases vascular permeability of human endothelial cell monolayers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1000852-57-2. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences.
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leukotriene-E4 20-monooxygenase
Also acts on N-acetyl-leukotriene E4, but more slowly. Not identical with EC 1.14.13.30 leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-E4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.34. CAS No. 111940-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0841; leukotriene-E4 20-monooxygenase; EC 1.14.13.34; 111940-51-3; leukotriene-E4 ω-hydroxylase. Cat No: EXWM-0841.
FPL 55712
FPL 55712 is a leukotriene receptor antagonist that inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Synonyms: FPL 55712; FPL55712; FPL-55712; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 40785-97-5. Molecular formula: C27H30O9. Mole weight: 498.52.
leukotriene-B4 20-monooxygenase
A heme-thiolate protein (P-450). Not identical with EC 1.14.13.34, leukotriene-E4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.30. CAS No. 90119-11-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0837; leukotriene-B4 20-monooxygenase; EC 1.14.13.30; 90119-11-2; leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Cat No: EXWM-0837.
LY 203647
LY 203647 is a a leukotriene D4 and E4 receptor antagonist with a tetrazole nucleus structure originated by Eli Lilly. No development for treatment of Ischaemic heart disorders by LY 203647 has been reported yet. Uses: Ischaemic heart disorders. Synonyms: LY 203647; LY203647; LY-203647; 1-(2-hydroxy-3-propyl-4-(4-(2-(4-(1H-tetrazol-5-yl)butyl)-2H-tetrazol-5-yl)butoxy)phenyl)-Ethanone. Grades: 98%. CAS No. 122009-61-4. Molecular formula: C21H30N8O3. Mole weight: 442.52.
LY 245769
LY 245769 is a leukotriene E4 (LTE4) inhibitor, and it can inhibit the oxidative degradation of LTE4 and N-acetyl-LTE4 in animal model. LY 245769, as one of the omega-trifluoro analogs of leukotrienes, will provide a new tool for interfering with the inactivation of leukotrienes in the omega-oxidation pathway. Synonyms: LY 245769; LY-245769; LY245769; R-(R*,S*-(E,Z)))-3-(1H-tetrazol-5-yl)-alpha-(14,14,14-trifluoro-1-((2-(1H-tetrazol-5-yl)ethyl)thio)-2,4-tetradecadienyl)-3-(1H-tetrazol-5-yl)-alpha-(14,14,14-trifluoro-1-((2-(1H-tetrazol-5-yl)ethyl)thio)-2,4-tetradecadienyl)-. Grades: 98%. CAS No. 127345-02-2. Molecular formula: C25H33F3N8OS. Mole weight: 550.65.
SR 2640 hydrochloride
SR 2640 hydrochloride is a potent and selective competitive leukotriene D4 and E4 receptor antagonist. SR 2640 has been shown to inhibit LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). It also inhibits LTD4-attenuation of human PMN chemotaxis. Synonyms: SR 2640 hydrochloride; SR2640 hydrochloride; SR-2640 hydrochloride; 2-[[3- (2-Quinolinylmethoxy) phenyl]amino]benzoic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 146662-42-2. Molecular formula: C23H18N2O3.HCl. Mole weight: 406.87.
SR 2640 Hydrochloride
Potent and selective competitive leukotriene D4 and E4 receptor antagonist. Inhibits LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). Also inhibits LTD4- attenuation of human PMN chemotaxis. Group: Biochemicals. Alternative Names: 2-[[3- (2-Quinolinylmethoxy) phenyl]amino]benzoic acid hydrochloride. Grades: Highly Purified. CAS No. 146662-42-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
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