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LGK974 LGK974 (WNT974) is an orally bioavailable and specific Porcupine (PORCN) inhibitor with an IC50 of 0.1 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WNT974. CAS No. 1243244-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17545. MedChemExpress MCE
LGK974 (LGK-974, WNT-974, LGK 974, NVP-LGK974) LGK974 is a highly potent inhibitor of Porcupine (PORCN), a Wnt-specific acyltransferase. LGK974 is orally bioavailable and inhibits WNT signaling in vitro and in vivo. It is reported to exhibit anti-tumor properties without increasing cytotoxicity. Group: Biochemicals. Alternative Names: 2-[5-methyl-6-(2-methylpyridin-4-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide; LGK-974; WNT-974; LGK 974; NVP-LGK974; 2’,3-Dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4’-bipyridine]-5-acetamide; 2-(2’,3-Dimethyl-[2,4’-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide. Grades: Highly Purified. CAS No. 1243244-14-5. Pack Sizes: 1mg, 5mg, 25mg, 100mg. Molecular Formula: C??H??N?O, Molecular Weight: 396.44. US Biological Life Sciences. USBiological 9
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