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| Product | Description | |
|---|---|---|
| Linopirdine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Linopirdine | Linopirdine (DuP 996) is an orally active, selective M-type K + current (IM; Kv7; KCNQ Channels) inhibitor with an IC 50 of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP 996. CAS No. 105431-72-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020468. |  |
| Linopirdine | Linopirdine is an enhancer of the release of several neurotransmitters, affecting neurotransmission and being used as a cognitive enhancer for the treatment of neurological disorders including Alzheimer's disease, Parkinsonism, and depression. It increases acetylcholine release in rat hippocampal CA1 neurons by blocking M-type (Kv7.2/7.3; KCNQ2/3) K+ current with an IC50 value of 2.4 μM. Uses: Potassium channel blockers. Synonyms: 2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-; 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one; DuP 996; 1-Phenyl-3,3-bis(4-pyridinylmethyl)-1,3-dihydro-2H-indol-2-one; 1-Phenyl-3,3-bis(pyridin-4-ylmethyl)-1,3-dihydro-2H-indol-2-one. Grades: ≥98%. CAS No. 105431-72-9. Molecular formula: C26H21N3O. Mole weight: 391.46. |  |
| Linopirdine dihydrochloride | Linopirdine dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 113168-57-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Linopirdine dihydrochloride | Linopirdine dihydrochloride is a blocker of KV7 voltage-gated potassium channels. It can block KV7.1 + 7.3 (KCNQ2 + 3) / M-currents with IC50 value from 4 to 7 μM and KV7.1 homomeric channels with IC50 value of 8.9 μM. Synonyms: Linopirdine Dihydrochloride; Linopirdine 2HCl; DuP-996 Dihydrochloride; DuP996 Dihydrochloride; DuP 996 Dihydrochloride; DuP-996 2HCl; DuP996 2HCl; DuP 996 2HCl; 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one dihydrochloride. Grades: ≥99% by HPLC. CAS No. 113168-57-3. Molecular formula: C26H21N3O.2HCl. Mole weight: 464.39. | |
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