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| Product | Description | |
|---|---|---|
| Linsitinib | Linsitinib, also known as OSI-906, is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Synonyms: OSI-906; OSI906; OSI 906. CAS No. 867160-71-2. Molecular formula: C26H23N5O. Mole weight: 421.504. |  |
| Linsitinib | Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent. Group: Biochemicals. Alternative Names: cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI 906; OSI 906AA. Grades: Highly Purified. CAS No. 867160-71-2. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Linsitinib | Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC 50 s of 35 and 75 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-906. CAS No. 867160-71-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10191. |  |
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