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LLL12 LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. LLL12 enhanced the inhibitory effect of Cisplatin (HY-17394) and Paclitaxel (HY-B0015) on ovarian cancer cell formation, migration, and growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1260247-42-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-19536. MedChemExpress MCE
LLL12 (5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide) A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells. Group: Biochemicals. Alternative Names: 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide. Grades: Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
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