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| Product | Description | |
|---|---|---|
| LLL12 | LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration and works synergistically with doxorubicin and gemcitabine. LLL12 demonstrated a potent inhibitory activity on breast and glioblastoma tumor growth in a mouse xenograft model. LLL12 may be a potential therapeutic agent for human cancer cells expressing constitutive STAT3 signaling. Synonyms: LLL12; LLL-12; LLL 12. CAS No. 1260247-42-4. Molecular formula: C14H9NO5S. Mole weight: 303.29. |  |
| LLL12 (5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide) | A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells. Group: Biochemicals. Alternative Names: 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide. Grades: Purified. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
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